S9132

Spiramycin

• Synonyme(s) : Rovamycin, Formacidine
• Numéro CAS: 8025-81-8
• Numéro CE : 232-429-6
• Numéro MDL: MFCD01314545
• Code UNSPSC : 51283208
• ID de substance PubChem : 24899826
• Nomenclature NACRES : NA.85

Propriétés

• Forme: powder
• Niveau de qualité: 200
• Activité optique: [α]/D -85 to -80° in water (Specific rotation (dry basis))
• Puissance: ≥4100 I.U. per mg (dry basis)
• Conditions de stockage: (Keep container tightly closed in a dry and well-ventilated place.)
• Couleur: white to light yellow
• Solubilité: methanol: soluble
• Traces de cations: heavy metals: ≤20 ppm
• Spectre d'activité de l'antibiotique: Gram-positive bacteria
• Mode d’action: protein synthesis | interferes
• Température de stockage: 2-8°C
• Chaîne SMILES: CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C
• InChI: 1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
• Clé InChI: ACTOXUHEUCPTEW-JMRHEKERSA-N

Description

Description générale

Chemical structure: macrolide

Application

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

Actions biochimiques/physiologiques

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

Qualité

A mixture of Spiramycin I, II and III.

Autres remarques

Keep container tightly closed in a dry and well-ventilated place.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)