R7882

Retinyl acetate

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

• Synonyme(s) : Acétate de rétinol
• Formule empirique (notation de Hill): C₂₂H₃₂O₂
• Numéro CAS: 127-47-9
• Poids moléculaire : 328.49
• Beilstein: 1915439
• Numéro CE : 204-844-2
• Numéro MDL: MFCD00019413
• Code UNSPSC : 12352205
• eCl@ss : 34058009
• ID de substance PubChem : 24899401
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 200
• Gamme de produits: BioReagent
• Essai: ≥90% (HPLC)
• Forme: solid or viscous liquid
• Puissance: ~2,800,000 I.U. per g
• Poids mol.: M_w 328.49 g/mol
• Technique(s): cell culture | mammalian: suitable
• Couleur: light yellow to dark yellow
• Pf: 57-58 °C
• Solubilité: absolute ethanol: 25 mg/mL (lit.)
• Température de stockage: −20°C
• Chaîne SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• Clé InChI: QGNJRVVDBSJHIZ-QHLGVNSISA-N

Description

Description générale

Retinyl-acetate is a natural and ester derivative of vitamin A. It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.

Application

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC) and as a supplement in the preparation of the complete medium.

Actions biochimiques/physiologiques

The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer.

Autres remarques

All trans

Notes préparatoires

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360D,H413
• Conseils de prudence: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Aquatic Chronic 4 - Repr. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 2
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter