MAB3729

Anti-c-met Antibody, clone 4AT44

clone 4AT44, Chemicon^®, from mouse

• Synonyme(s) : Hepatocyte Growth Factor Receptor, HGFR
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 4AT44, monoclonal
• Espèces réactives: mouse, human
• Fabricant/nom de marque: Chemicon^®
• Technique(s): western blot: suitable
• Isotype: IgG1
• Numéro d'accès NCBI: NP_000236.2
• Numéro d'accès UniProt: P08581
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... MET(4233) ; mouse ... Met(17295)

Description

Spécificité

Reacts with c-met/HGFR (Hepatocyte growth factor receptor). The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.

Immunogène

Purified recombinant catalytic domain of human Met

Application

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-c-met Antibody, clone 4AT44 is validated for use in WB for the detection of c-met.

Western Blot: 1:100-1:500.

ELISA (direct): 1:1,000

Optimal working dilutions must be determined by the end user.

Liaison

Replaces: 04-1051

Forme physique

Format: Purified

Protein G purified immunoglobulin. Liquid in PBS containing 0.09% sodium azide.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable