Accéder au contenu
Merck
Toutes les photos(1)

Documents

K2755

Sigma-Aldrich

2-Keto-3-deoxyoctonate ammonium salt

≥97%

Synonyme(s) :

3-Deoxyoctulosonic acid, KDO

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule linéaire :
C8H14O8 · NH3
Numéro CAS:
103404-70-2
Poids moléculaire :
255.22
Numéro MDL:
MFCD00057549
Code UNSPSC :
12352100
ID de substance PubChem :
57654316
Nomenclature NACRES :
NA.22

Pureté

≥97%

Forme

powder

Température de stockage

−20°C

Chaîne SMILES 

N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O

InChI

1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3

Clé InChI

UDJBBKGYARWWNJ-UHFFFAOYSA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

  • Synthesis of KDO Analogues: A significant study focused on the synthesis of analogues of 3-deoxy-D-manno-octulosonic acid (KDO), which includes compounds such as 2-Keto-3-deoxyoctonate ammonium salt. These analogues were evaluated as potential inhibitors of CMP-KDO synthetase, playing a critical role in the development of new therapeutic agents targeting bacterial infections and enhancing understanding of bacterial lipopolysaccharide synthesis (Luthman et al., 1987).

Actions biochimiques/physiologiques

KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 2

1 of 2

N-Acetylneuraminic acid ≥95% anhydrous basis, synthetic

Sigma-Aldrich

A0812

N-Acetylneuraminic acid

Periodic acid ReagentPlus®, ≥99.0%

Sigma-Aldrich

P7875

Periodic acid

Laura Cipolla et al.
Current drug discovery technologies, 6(1), 19-33 (2009-03-12)
Despite important advances made in the last century, infectious diseases caused by pathogenic microrganisms are still a major threat to human health. This is worsened by the occurrence of new forms of bacterial resistance against antibiotics, that are the main
Cadi Davies et al.
Frontiers in cellular and infection microbiology, 9, 177-177 (2019-06-14)
Campylobacter jejuni outer membrane vesicles (OMVs) contain numerous virulence-associated proteins including the cytolethal distending toxin and three serine proteases. As C. jejuni lacks the classical virulence-associated secretion systems of other enteric pathogens that deliver effectors directly into target cells, OMVs
Aloka B Bandara et al.
PloS one, 6(4), e19003-e19003 (2011-05-06)
Francisella tularensis is a category-A select agent and is responsible for tularemia in humans and animals. The surface components of F. tularensis that contribute to virulence are not well characterized. An electron-dense capsule has been postulated to be present around
Leticia Martínez-Lapuente et al.
Food research international (Ottawa, Ont.), 96, 235-243 (2017-05-22)
The effect of egg albumin fining, progressive clarification and cross-flow microfiltration on the polysaccharide and proanthocyanidin composition of four red varietal wines was studied in this work. Discriminant analyses were applied to achieve a possible differentiation of the wines according
Blanka Bucsella et al.
Analytical methods : advancing methods and applications, 12(38), 4621-4634 (2020-09-15)
The paper presents a novel instrumental analytical endotoxin quantification assay. It uses common analytical laboratory equipment (HPLC-FLD) and allows quantifying endotoxins (ETs) in different matrices from about 109 EU per mL down to about 40 EU per mL (RSE based).
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique