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Merck
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Principaux documents

P7875

Sigma-Aldrich

Periodic acid

ReagentPlus®, ≥99.0%

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About This Item

Formule empirique (notation de Hill) :
H5IO6
Numéro CAS:
Poids moléculaire :
227.94
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352106
ID de substance PubChem :
Nomenclature NACRES :
NA.21
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Qualité

reagent

Gamme de produits

ReagentPlus®

Essai

≥99.0%

Forme

powder or crystals

Pertinence de la réaction

reagent type: oxidant

Technique(s)

toxicology assay: suitable

Pf

122 °C (lit.)

Solubilité

water: 100 mg/mL, clear, colorless

Chaîne SMILES 

OI(O)(O)(O)(O)=O

InChI

1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)

Clé InChI

TWLXDPFBEPBAQB-UHFFFAOYSA-N

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Description générale

Periodic acid, an oxoacid of iodine, is commonly used as a strong oxidizing agent. This inorganic acid is soluble in most solvents including water and ether.

Application

Periodic acid can be used in the following reactions:      
  • Oxidation of alcohols to ketones and aldehydes.
  • Oxidation hydroxylamine derivatives.    
  • Oxidation of arenes to quinones.

It can also be used:     
  • As a stoichiometric oxidant with chromium (IV) acetate for the oxidation of tertiary C−H bonds to tertiary alcohols.     
  • In combination with chromium oxide to oxidize primary alcohols to carboxylic acids; alkylbenzenes to benzoic acids; and cyclic benzyl ethers to the corresponding lactones.      
  • In the selective oxidation of sulfides to sulfoxides using FeCl3 as a catalyst.

Informations légales

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1B - STOT RE 1 Oral

Organes cibles

Thyroid

Code de la classe de stockage

5.1A - Strongly oxidizing hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Zollie A Yavarow et al.
Human molecular genetics, 29(2), 286-294 (2019-12-10)
Glycogen storage disease type Ia (GSD Ia) is caused by autosomal mutations in glucose-6-phosphatase α catalytic subunit (G6PC) and can present with severe hypoglycemia, lactic acidosis and hypertriglyceridemia. In both children and adults with GSD Ia, there is over-accumulation of
Murad Alturkustani et al.
Journal of neuropathology and experimental neurology, 74(3), 233-240 (2015-02-11)
The pathologic features of adult-onset leukoencephalopathy/leukodystrophy with axonal spheroids (ALAS) are variable, and this has led to different hypotheses as to whether primarily demyelination or axonopathy may underlie this disorder. Typical ALAS pathology is rarely accompanied by focal multiple sclerosis
D Canbaz et al.
Allergy, 70(5), 522-532 (2015-02-14)
The initial immune response to house dust mite (HDM) is orchestrated by an interplay between epithelial cells (ECs) and dendritic cells (DCs). Innate cytokines released by HDM-exposed ECs activate airway DCs and effector inflammatory cells, which together induce a HDM-specific
Dmitriy Berillo et al.
Macromolecular bioscience, 12(8), 1090-1099 (2012-06-08)
Macroporous scaffolds composed of chitosan and using oxidized dextran as a crosslinker are produced through cryogelation. Introducing gelatin as a third component into the structure results in the formation of mesopores in the pore walls, which are not seen if
Lance A Thielen et al.
Cell metabolism, 32(3), 353-365 (2020-07-30)
Diabetes is characterized by hyperglycemia, loss of functional islet beta cell mass, deficiency of glucose-lowering insulin, and persistent alpha cell secretion of gluconeogenic glucagon. Still, no therapies that target these underlying processes are available. We therefore performed high-throughput screening of

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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