900865

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Synonyme(s) : Formyl sulfonyl fluoride TMS-Alkyne, Probe building block
• Formule empirique (notation de Hill): C₁₂H₁₃FO₃SSi
• Numéro CAS: 2088829-01-8
• Poids moléculaire : 284.38
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: ≥95%
• Forme: powder or crystals
• Capacité de réaction: reaction type: click chemistry
• Température de stockage: −20°C
• Chaîne SMILES: O=CC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

Description

Application

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Autres remarques

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable