900683

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine

95%

• Synonyme(s) : Amino diazirine alkyne, Probe building block
• Formule empirique (notation de Hill) : C₇H₁₁N₃
• Numéro CAS: 1450752-97-2
• Poids moléculaire : 137.18
• Numéro MDL: MFCD29918288
• Code UNSPSC : 12352116

Propriétés

• Niveau de qualité: 100
• Essai: 95%
• Forme: liquid
• Température de stockage: −20°C
• Chaîne SMILES: NCCC1(N=N1)CCC#C
• Clé InChI: FMCIBERQJQEYIZ-UHFFFAOYSA-N

Description

Application

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Autres remarques

Technology Spotlight: Trifuctional Probe Building Blocks

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

"Minimalist" Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Danger
• Mentions de danger: H242
• Conseils de prudence: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classification des risques: Self-react. C
• Code de la classe de stockage: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable