mAbs Characterization & Quality Control
The key for ensuring drug safety and efficacy
Characterization and quality control of monoclonal antibodies (mAbs) is essential to ensure their efficacy and safety. Analytical techniques, like HPLC and mass spectrometry, are vital to assess various properties, such as aggregation, charge variants, and post-translational modifications (PTMs). Our extensive selection of products supports the detailed analysis and evaluation of mAbs to maintain quality and effectiveness.
Post-Translational Modification Analysis of Monoclonal Antibodies
Post-translational modification analysis of monoclonal antibodies (mAbs) assesses product consistency, efficacy, and safety. To identify and quantify PTMs in mAbs, mass spectrometry and chromatography are commonly used. High-purity solvents are used to prevent contamination and ensure consistency. HPLC columns separate and quantify different components of the mAb sample. Analytical reagents are used for characterization and detection of mAbs. Glycobiology profiling tools are used to analyze the carbohydrate structures of mAbs.
We offer all the tools you need to monitor and ensure the consistency, quality, and safety of mAbs across various stages of the mAb production workflow.
Related Categories
Explore RPC, SEC, IEC, HILIC, and IMAC columns.
Use our highest grade of solvents in mAb production to minimize the risk of impurities.
Count on our high-quality reagents for analytical characterization in various stages of mAb production.
Find glycosidases and glycobiology reagents and kits to support glycobiology profiling of mAbs.
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HPLC separates and identifies large biomolecules like proteins and peptides by pumping the sample through a sorbent-packed column.
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Learn about the advantages of these columns compared to commercial FPP columns for large molecule separation.
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Related Webinars
Discover how to maximize efficiency and resolution when using reversed phase chromatography (RPC) and size exclusion chromatography (SEC).
Learn how to enable and maintain high quality and high sensitivity in LC-MS analyses by preventing impurities and contaminations.
Explore a simple and high throughput method for the quantitation of monoclonal antibodies and proteins in human and animal serum.
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