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RAB0671

Human GCG / Glucagon ELISA Kit

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... GCG(2641)
Input:
sample type plasma
sample type serum
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
Pricing and availability is not currently available.
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.5 pg/mL
standard curve range: 2.03-130 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GCG(2641)

General description

Glucagon-like peptide-1 (GLP-1), a peptide hormone is liberated from endocrine epithelial cells of the small intestine.[1] The proglucagon gene (GCG) codes for glucagon, glucagon-like peptide-1 (GLP-1), and glucagon-like peptide-2 (GLP-2).[2]

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Glucagon-like peptide-1 (GLP-1) treatment helps to lower the risk of stroke in diabetic patients and to be neuroprotective in experimental stroke models.[1] It participates in glucose homeostasis and has an impact on the cardiovascular system.[3] GLP-1 may promote pancreatic β-cell proliferation and neogenesis. It enhances insulin release after a meal and triggers insulin transcription and biosynthesis.[2]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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This Item
EZGLP1TRAB0666RAB0667
Gene Information

human ... GCG(2641)

Gene Information

human ... GCG(2641)

Gene Information

human ... GCG (1-36a)(2641)

Gene Information

human ... GCG (1-37)(2641)

species reactivity

human

species reactivity

human, mouse, rat

species reactivity

human

species reactivity

human

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.5 pg/mL
standard curve range: 2.03-130 pg/mL

assay range

-

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 150 pg/mL
standard curve range: 312.5-20000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.3 pg/mL
standard curve range: 2.34-150 pg/mL

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

input

sample type cell culture supernatant
sample type plasma (K2 EDTA)
sample type serum

input

sample type cell culture supernatant(s)
sample type serum
sample type plasma

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

detection method

colorimetric

detection method

colorimetric (450nm/590nm)

detection method

colorimetric

detection method

colorimetric

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable


Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certificates of Analysis (COA)

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Related Content


Tianru Jin
The Journal of endocrinology, 198(1), 17-28 (2008-06-26)
The proglucagon gene (gcg) encodes a number of peptide hormones that are of cell-type specifically expressed in the pancreatic islets, the distal ileum and the large intestine, as well as certain brain neuronal cells. These hormones are important in controlling
Charles-Étienne Plourde et al.
Obesity (Silver Spring, Md.), 22(8), 1838-1846 (2014-04-25)
To assess the rapid improvement of insulin sensitivity and β-cell function following biliopancreatic diversion with duodenal switch (BPD-DS) and determine the role played by caloric restriction in these changes. Standard meals were administrated before and on day 3, 4, and
David R Powell et al.
The Journal of pharmacology and experimental therapeutics, 350(2), 232-242 (2014-05-23)
Treatments that lower blood glucose levels and body weight should benefit patients with type 2 diabetes mellitus (T2DM). We developed LX4211 [(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol], an orally available small molecule that decreases postprandial glucose excursions by inhibiting intestinal sodium/glucose cotransporter 1 (SGLT1) and



Global Trade Item Number

SKUGTIN
RAB0671-1KT04061835164608

Questions

  1. What's the target of this ELISA? only 29 amino acid glucagon or all peptides that contains these 29 amino acid (e.g., Oxyntomodulin, proglucagon)?

    1 answer
    1. This ELISA antibody pair specifically detects the 29-amino-acid sequence of glucagon. However, detection of oxyntomodulin or proglucagon has not been validated.

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