Key Documents

Dicyclomine hydrochloride

Name: Dicyclomine hydrochloride
Brand: SIGMA

≥99% (TLC), powder

Synonym(s):

2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride, [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₃₅NO₂ · HCl

CAS Number:

67-92-5

Molecular Weight:

345.95

NACRES:

NA.77

PubChem Substance ID:

24278385

UNSPSC Code:

41116107

EC Number:

200-671-1

MDL number:

MFCD00079158

Assay:

≥99% (TLC)

Form:

powder

Quality level:

200

Pricing and availability is not currently available.

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Properties

Quality Level

200

assay

≥99% (TLC)

form

powder

color

off-white

solubility

H₂O: 50 mg/mL

SMILES string

CCN(CCOC(C1(C2CCCCC2)CCCCC1)=O)CC.[Cl]

InChI

1S/C19H35NO2.ClH/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17;/h17H,3-16H2,1-2H3;1H

InChI key

GUBNMFJOJGDCEL-UHFFFAOYSA-N

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Description

Biochem/physiol Actions

Competitive muscarinic acetylcholine receptor antagonist.

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This Item	O2881	SML2774	SML1925
Sigma-Aldrich D7909 Dicyclomine hydrochloride	Sigma-Aldrich O2881 Oxybutynin chloride	Sigma-Aldrich SML2774 KDOAM25 hydrochloride hydrate	Sigma-Aldrich SML1925 Bepristat 2a hydrochloride
form powder	form powder	form powder	form powder
assay ≥99% (TLC)	assay ≥98% (TLC)	assay ≥98% (HPLC)	assay ≥95% (HPLC)
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
solubility H₂O: 50 mg/mL	solubility H₂O: 50 mg/mL	solubility H₂O: 2 mg/mL, clear	solubility H₂O: 10 mg/mL, clear
color off-white	color white	color white to beige	color white to beige
Gene Information human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)	Gene Information human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)	Gene Information -	Gene Information -

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pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

0000558806

0000476397

0000459460

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American Gastroenterological Association institute medical position statement on the use of gastrointestinal medication in pregnancy.

Arthur Staroselsky et al.

Gastroenterology, 132(2), 824-825 (2007-01-31)

Task demands dissociate the effects of muscarinic M1 receptor blockade and protein kinase C inhibition on attentional performance in rats.

Andrea M Robinson et al.

Journal of psychopharmacology (Oxford, England), 26(8), 1143-1150 (2011-09-06)

The cholinergic system is known to be necessary for normal attentional processing. However, the receptors and mechanisms mediating the effects of acetylcholine on attention remain unclear. Previous work in our laboratory suggested that cholinergic muscarinic receptors are critical for maintaining

A computer-automated touchscreen paired-associates learning (PAL) task for mice: impairments following administration of scopolamine or dicyclomine and improvements following donepezil.

Susan J Bartko et al.

Psychopharmacology, 214(2), 537-548 (2010-11-19)

Performance on the Cambridge Neuropsychological Test Automated Battery touchscreen paired-associates learning (PAL) test is predictive of Alzheimer's disease and impaired in schizophrenia and chronic drug users. An automated computer touchscreen PAL task for rats has been previously established. A pharmacologically

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Global Trade Item Number

SKU	GTIN
D7909-5G	04061833588970

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