This product has not been tested for suitability in the Ellman's Assay, however it has been cited in the publication below. In addition, see product D8130, DTNB Ellman's reagent.
Cholinesterase assay by an efficient fixed time endpoint method
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473035/
A5751
Acetylthiocholine iodide
≥98% (TLC), powder or crystals
Synonym(s):
(2-Mercaptoethyl)trimethylammonium iodide acetate
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| Pack Size | SKU | Availability | Price |
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About This Item
Linear Formula:
CH3COSCH2CH2N(CH3)3I
CAS Number:
Molecular Weight:
289.18
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
EC Number:
217-474-1
Beilstein/REAXYS Number:
3916578
MDL number:
Pricing and availability is not currently available.
assay
≥98% (TLC)
form
powder or crystals
color
white
mp
205-210 °C (lit.)
solubility
H2O: 100 mg/mL
storage temp.
2-8°C
SMILES string
[I-].CC(=O)SCC[N+](C)(C)C
InChI
1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key
NTBLZMAMTZXLBP-UHFFFAOYSA-M
General description
Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.
Application
Substrate for the colorimetric determination of acetylcholinesterase activity.
Acetylthiocholine iodide has been used as a substrate in the preparation of acetylcholine esterase (AChE) assay working solution for AChE activity assay. It has also been used as a component in phosphate buffer (PB) for cholinesterase assay.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥98% (TLC) | assay ≥99% (TLC) | assay ≥99.0% (AT) | assay ≥99.0% (AT) |
| solubility H2O: 100 mg/mL | solubility water: 100 mg/mL, clear to slightly hazy, colorless | solubility - | solubility H2O: 1 M, clear, colorless |
| form powder or crystals | form powder | form crystalline | form powder or crystals |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| color white | color - | color - | color colorless to white |
| mp 205-210 °C (lit.) | mp - | mp 171-174 °C | mp 302-305 °C (dec.) (lit.) |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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An integrated addition and interaction model for assessing toxicity of chemical mixtures
Rider CV and LeBlanc GA
Toxicological Sciences, 87(2), 520-528 (2005)
Anti-acetylcholinesterase activities of traditional Chinese medicine for treating Alzheimer's disease
Lin HQ, et al.
Chemico-Biological Interactions, 175(1-3), 352-354 (2008)
The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space
Perez GR, et al.
The Journal of Biological Chemistry, 287(51), 43108-43115 (2012)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A5751-25G | 04061833376294 |
| A5751-5G | 04061835553518 |
| A5751-250MG | 04061833376287 |
| A5751-1G | 04061835553501 |
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Is the powder form of Acetylthiocholine iodide suitable for Ellman's assay or do you have to prepare it into a solution? If so, do you have any guide on how to prepare it into a solution?
1 answer-
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