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A1394

4-Aminophenyl α-D-mannopyranoside

≥98% (TLC)

Synonym(s):

p-aminophenyl alpha-D-mannoside

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About This Item

Empirical Formula (Hill Notation):
C12H17NO6
CAS Number:
Molecular Weight:
271.27
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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Quality Level

assay

≥98% (TLC)

form

powder

optical activity

[α]/D 123.00 to 135.00°, c = 9.00-11.00 mg/mL in methanol

technique(s)

thin layer chromatography (TLC): suitable

color

white to yellow cast

solubility

H2O: soluble

storage temp.

2-8°C

SMILES string

Nc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1

InChI

1S/C12H17NO6/c13-6-1-3-7(4-2-6)18-12-11(17)10(16)9(15)8(5-14)19-12/h1-4,8-12,14-17H,5,13H2

InChI key

MIAKOEWBCMPCQR-UHFFFAOYSA-N

Application

4-Aminophenyl α-D-mannopyranoside is used to modify the surface of liposomes to increase uptake kinetics.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item
M9271G0259I5502
technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

assay

≥98% (TLC)

assay

>98% (TLC)

assay

≥98% (TLC)

assay

≥99% (TLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200, 300

solubility

H2O: soluble

solubility

50 mg/mL, clear to very slightly hazy, colorless to light yellow (ACETONE:DIMETHYL SULFOXIDE (7:3))

solubility

0.5 M HCl: 50 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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M Triggiani et al.
Journal of immunology (Baltimore, Md. : 1950), 164(9), 4908-4915 (2000-04-26)
Secretory phospholipases A2 (sPLA2s) are a group of extracellular enzymes that release fatty acids at the sn-2 position of phospholipids. Group IIA sPLA2 has been detected in inflammatory fluids, and its plasma level is increased in inflammatory diseases. To investigate
Xue Ying et al.
Pharmacology, 87(1-2), 105-114 (2011-02-02)
To circumvent the problem of transporting anticancer drugs across the blood-brain barrier (BBB) to target brain tumors, we have previously developed dual-targeting daunorubicin liposomes modified with 4-aminophenyl-α-D-manno-pyranoside and transferrin molecules. The objective of the present study was to evaluate the
Sumio Chono et al.
Drug development and industrial pharmacy, 36(1), 102-107 (2009-08-07)
The effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages (AMs) was evaluated in vitro and in vivo. 4-Aminophenyl-α-D-mannopyranoside (Man) was used for surface-mannose modification, and mannosylated liposomes with various mannosylation rates (particle size: 1000 nm) were prepared.



Global Trade Item Number

SKUGTIN
A1394-50MG04061832386614
A1394-250MG04061832386607
A1394-10MG04061832386591

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