90335

Triethylamine

BioUltra, ≥99.5% (GC)

• Synonym(s): N,N-Diethylethanamine
• Linear Formula: (C₂H₅)₃N
• CAS Number: 121-44-8
• Molecular Weight: 101.19
• UNSPSC Code: 12352116
• NACRES: NA.25
• PubChem Substance ID: 57653384
• EC Number: 204-469-4
• Beilstein/REAXYS Number: 605283
• MDL number: MFCD00009051
• Assay: ≥99.5% (GC)
• Technique(s): ion chromatography: suitable
• Bp: 88.8 °C (lit.)
• Vapor pressure: 51.75 mmHg ( 20 °C)

Properties

• vapor density: 3.5 (vs air)
• Quality Segment: 200
• vapor pressure: 51.75 mmHg ( 20 °C)
• product line: BioUltra
• assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 593 °F
• shelf life: 36 mo.
• expl. lim.: 8 %
• technique(s): ion chromatography: suitable
• impurities: insoluble matter, passes filter test, ≤0.5% water
• evapn. residue: ≤0.003%
• refractive index: n20/D 1.401 (lit.)
• pH: 12.7 (15 °C, 100 g/L)
• bp: 88.8 °C (lit.)
• mp: −115 °C (lit.)
• density: 0.726 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.2 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.1 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.05 mg/kg, Co: ≤0.02 mg/kg, Cr: ≤0.02 mg/kg, Cu: ≤0.02 mg/kg, Fe: ≤0.1 mg/kg, K: ≤0.5 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤0.1 mg/kg, Mn: ≤0.02 mg/kg, Mo: ≤0.02 mg/kg, Na: ≤0.5 mg/kg, Ni: ≤0.02 mg/kg, Pb: ≤0.1 mg/kg, Sr: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg
• absorption: cut-off at 278 nm
• storage temp.: room temp
• SMILES string: CCN(CC)CC
• InChI: 1S/C6H15N/c1-4-7(5-2)6-3/h4-6H2,1-3H3
• InChI key: ZMANZCXQSJIPKH-UHFFFAOYSA-N

Description

General description

Triethyl amine (TEA) is an aliphatic tertiary amine.

Application

Triethylamine has been used to bind the n-hydroxysuccinimide (NHS) group with the amino-treated tip surface. It has also been used as a basic catalyst for acylation.

Biochem/physiol Actions

Triethylamine (TEA) may play a dual role as a base and a solubilizing agent for promoting the reaction in toluene and TEA.

Triethylamine, a mobile-phase modifier, is used in the reversed-phase high-performance liquid chromatography (RP-HPLC) separation of acidic, basic, and neutral molecules. It improves the resolution of amino acids and amino acids amides by suppressing the tailing and the stability of drugs and other compounds.

Other Notes

Component of volatile buffer system in ion-exchange HPLC of oligonucleotides[1]

Safety Information

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• flash_point_f: 12.2 °F - closed cup
• flash_point_c: -11 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
• hcodes: H225,H301 + H311 + H331,H314,H335
• pcodes: P210 - P280 - P301 + P310 + P330 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3