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45698

Trichlorfon

PESTANAL®, analytical standard

Synonym(s):

(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester, Metrifonate

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About This Item

Empirical Formula (Hill Notation):
C4H8Cl3O4P
CAS Number:
Molecular Weight:
257.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-149-3
Beilstein/REAXYS Number:
1709434
MDL number:
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grade

analytical standard

Quality Segment

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

application(s)

agriculture
environmental

format

neat

storage temp.

2-8°C

SMILES string

COP(=O)(OC)C(O)C(Cl)(Cl)Cl

InChI

1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3

InChI key

NFACJZMKEDPNKN-UHFFFAOYSA-N

Biochem/physiol Actions

Trichlorfon also known as metrifonate, is an insecticide that functions as an inhibitor of acetylcholine esterase. Trichlorfon has been shown to induce DNA damage and genetic defects in numerous cell lines in addition to inducing aneuploidy in male mouse germ cells. [1]

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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format

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analytical standard

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certified reference material, TraceCERT®

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grade

pharmaceutical primary standard

product line

PESTANAL®

product line

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product line

TraceCERT®

product line

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300

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300

Quality Level

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storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

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shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

-


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signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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F Y Sun et al.
Mutagenesis, 15(1), 17-24 (2000-01-21)
In order to assess the effects of trichlorfon on cell division and on aneuploidy induction, we conducted an in vitro assay for spindle disturbances using V79 cells and an in vivo assay for aneuploidy induction in meiosis of male mice
Amit Kumar Sinha et al.
Comparative biochemistry and physiology. Part D, Genomics & proteomics, 5(3), 207-216 (2010-06-24)
Trichlorfon (TRC) is the most common organophosphorous insecticide used in aquaculture practices in Southeast Asian countries. Indiscriminate use of TRC can either damage or alter the enzymatic and hormonal activities in the living organisms. In this present study, therefore, toxicogenomic
Tao Jin et al.
Pest management science, 67(3), 370-376 (2011-02-11)
In order to investigate the extent of resistance of oriental fruit fly, Bactrocera dorsalis (Hendel), which is a widespread pest throughout tropical, subtropical and temperate fruit crops, 25 populations of this insect were collected from 13 sites in mainland China



Global Trade Item Number

SKUGTIN
45698-250MG-R04061832341804
45698-50MG-R04061832341811

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