Saltar al contenido
MilliporeSigma
Todas las fotos(2)

Documentos

M5696

Sigma-Aldrich

Myoglobin from equine skeletal muscle

BioUltra, 95-100% (SDS-PAGE)

Sinónimos:

Myoglobin from horse skeletal muscle

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(2)

About This Item

Número de CAS:
100684-32-0
EC Number:
309-705-0
MDL number:
MFCD00131643
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

equine skeletal muscle

product line

BioUltra

assay

95-100% (SDS-PAGE)

form

essentially salt-free, lyophilized powder

mol wt

~17 kDa(lit.)

purified by

affinity chromatography

Iron content content

~0.30%

technique(s)

mass spectrometry (MS): suitable

solubility

H2O: soluble 10 mg/mL

UniProt accession no.

P68082

storage temp.

−20°C

Gene Information

horse ... MB(100054434)

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Myoglobin from equine skeletal muscle has been used to induce acute kidney injury (AKI) in mice. It has also been used as a standard for top down mass spectrometry.
Myoglobin is used as a molecular weight marker and a standard for mass spectroscopy and X-ray crystallography.Myoglobin from equine skeletal muscle was used in a study to test experimental protein mixture for validating tandem mass spectral analysis.

Biochem/physiol Actions

Myoglobin from horse skeletal muscle is a single chain heme protein containing 153 amino acid residues. It possesses no disulfide bridges or free -SH groups. Myoglobin contains 8 variously sized right-handed helical regions, joined by non-ordered or random coil regions.
Myoglobin is critical to skeletal muscle O2 supply at near-maximum oxygen demand, and prevents anoxia by maintaining PO2 above levels needed to support mitochondrial function.
Myoglobin is critical to skeletal muscle O2 supply at near-maximum oxygen demand, and prevents anoxia by maintaining PO2 above levels needed to support mitochondrial function.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

S C Powell et al.
Journal of chromatography, 317, 87-92 (1984-12-28)
Urine and serum myoglobin have been separated on an anion-exchange column, packed by the slurry technique. Urine or serum was injected directly into the column and eluted isocratically with Tris buffer. Freshly prepared myoglobin from human muscle gives two peaks
Seok Jong Song et al.
International journal of molecular sciences, 21(22) (2020-11-19)
A recent study showed that early renal tubular injury is ameliorated in Nod-like receptor pyrin domain-containing protein 3 (NLRP3) KO mice with rhabdomyolysis-induced acute kidney injury (RIAKI). However, the precise mechanism has not been determined. Therefore, we investigated the role
Z K Shihabi
Journal of chromatography. B, Biomedical applications, 669(1), 53-58 (1995-07-07)
Capillary electrophoresis was used in this study to separate urinary myoglobin from hemoglobin based on its electrophoretic mobility. Urine was applied directly without any treatment. The separation was accomplished in less than 7 min. Myoglobin extracted from human muscle tissues
Protein Bioinformatics (2017)
Rhabdomyolysis induced AKI via the regulation of endoplasmic reticulum stress and oxidative stress in PTECs
Feng Y, et al.
Royal Society of Chemistry Advances, 6(111), 109639-109648 (2016)
Ver todos los artículos relacionados

Artículos

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

2D Materials in Biosensing

Professors summarize recent 2D materials synthesis advancements and biosensing applications in various fields.

Chromatograms

application for HPLC

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico