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MilliporeSigma

A4544

Sigma-Aldrich

Ácido L-ascórbico

suitable for cell culture, suitable for plant cell culture, ≥98%

Sinónimos:

Ácido L-treoascórbico, Factor antiescorbútico, Vitamina C

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About This Item

Fórmula empírica (notación de Hill):
C6H8O6
Número de CAS:
Peso molecular:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

Quality Level

assay

≥98%

form

powder

mol wt

Mw 176.12 g/mol

technique(s)

cell culture | mammalian: suitable
cell culture | plant: suitable

color

white to light yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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General description

L-ascorbic acid also called vitamin C, is a water soluble vitamin and acts as a reducing agent for various biochemical reactions. Ascorbic acid plays a key role in the production of collagen. Ascorbic acid is essential for neurodevelopment, neurotransmitter synthesis and modulates neuronal synapsis. Dietary inadequacy of vitamin C has negative impact on cognition.

Application

L-ascorbic acid has been used as an ingredient in the basal medium for bovine mammary epithelial cells and oocyte-granulosa cell complexes. It has been used as a supplement in the osteogenic medium for osteogenic differentiation.

Biochem/physiol Actions

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Wystrychowski W, et al.
Stem Cell Research & Therapy, 7(1), 84-84 (2016)
Mitochondrial dysfunction of in vitro grown rabbit oocytes results in preimplantation embryo arrest after activation
Kanaya H, et al.
Journal of Reproduction and Development, 53(3), 631-637 (2007)
Vitamin C status and cognitive function: A systematic review
Travica N, et al.
Nutrients, 9(9), 960-960 (2017)
Does vitamin C deficiency affect cognitive development and function?
Hansen SN, et al.
Nutrients, 6(9), 3818-3846 (2014)

Artículos

Importance and uses of ascorbate in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

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