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SML2462

Sigma-Aldrich

HZ-166

≥98% (HPLC)

Synonym(s):

8-Ethynyl-6-(2-pyridinyl)-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester

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5 MG
$55.75
25 MG
$245.00

$55.75

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Available to ship onMarch 28, 2025Details

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5 MG
$55.75
25 MG
$245.00

About This Item

Empirical Formula (Hill Notation):
C21H16N4O2
CAS Number:
612527-56-7
Molecular Weight:
356.38
UNSPSC Code:
12352200
NACRES:
NA.77

$55.75

List Price$60.40Save 8%

Available to ship onMarch 28, 2025Details

Request a Bulk Order

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

C#CC1=CC=C2C(C(C3=NC=CC=C3)=NCC4=C(C(OCC)=O)N=CN42)=C1

InChI key

ZSEDMNMFODMQRD-UHFFFAOYSA-N

Biochem/physiol Actions

HZ-166 is a potent, non-sedative GABAA receptor subtype-selective benzodiazepine site agonist exhibits preference toward α2- and α3-GABAARs. HZ-166 exhibits antihyperalgesic properties in mice models of neuropathic and inflammatory pain, without sedation and motor impairment.
potent, non-sedative GABAA receptor subtype-selective benzodiazepine site agonist exhibits preference toward α2- and α3-GABAARs

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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