SML0707

FKGK11

≥98% (GC)

• Synonym(s): 1,1,1,2,2-Pentafluoro-7-phenyl-3-Heptanone
• Empirical Formula (Hill Notation): C₁₃H₁₃F₅O
• CAS Number: 1071000-98-0
• Molecular Weight: 280.23
• UNSPSC Code: 41106300
• NACRES: NA.77

Properties

• assay: ≥98% (GC)
• form: oil
• color: colorless to yellow
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C13H13F5O/c14-12(15,13(16,17)18)11(19)9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9H2
• InChI key: ROPVXAWEVYWEQY-UHFFFAOYSA-N

Description

Biochem/physiol Actions

FKGK11 is a potent inhibitor of GVIA iPLA2 with little or no inhibition against GIVA cPLA2 (XI(50) = 0.0073 and >0.91, respectively).

FKGK11 is a potent inhibitor of GVIA iPLA2 with little or no inhibition against GIVA cPLA2 (XI(50) = 0.0073 and >0.91, respectively). The compound displays a slight inhibition against GVsPLA2. FKGK11 potently inhibited the progression and severity in a murine experimental autoimmune encephalomyelitis (EAE) model.

Features and Benefits

This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Air sensitive; suggest to store under nitrogen in freezer.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable