SAB4300139

Anti-phospho-SNCA (pSer¹²⁹) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-MGC110988 antibody produced in rabbit, Anti-NACP antibody produced in rabbit, Anti-PARK1 antibody produced in rabbit, Anti-PARK4 antibody produced in rabbit, Anti-synuclein, alpha (non A4 component of amyloid precursor) antibody produced in rabbit
• MDL number: MFCD02095740
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~18 kDa
• species reactivity: mouse, rat, human
• concentration: 1 mg/mL
• technique(s): western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (M-P-SP-E-E)
• NCBI accession no.: NP_000336.1
• UniProt accession no.: P37840
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer129)
• Gene Information: human ... SNCA(6622)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 129 (M-P-S(p)-E-E), according to the protein SNCA.

Features and Benefits

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Target description

May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable