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S7382

Sigma-Aldrich

Sulfaquinoxaline sodium salt

≥92.5%

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About This Item

Empirical Formula (Hill Notation):
C14H11N4NaO2S
CAS Number:
967-80-6
Molecular Weight:
322.32
Beilstein/REAXYS Number:
290026
EC Number:
213-526-2
MDL number:
MFCD00799608
UNSPSC Code:
51283953
PubChem Substance ID:
24899740
NACRES:
NA.85

assay

≥92.5%

form

powder

color

white to yellow

solubility

H2O: soluble 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

mode of action

DNA synthesis | interferes
enzyme | inhibits

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Na])c2cnc3ccccc3n2

InChI

1S/C14H11N4O2S.Na/c15-10-5-7-11(8-6-10)21(19,20)18-14-9-16-12-3-1-2-4-13(12)17-14;/h1-9H,15H2;/q-1;+1

InChI key

WXUQBKOBXREBBX-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide

Application

Sulfaquinoxaline is a veterinary medicine used to treat coccidiosis. It is a protective agent against upper respiratory infections of poultry and a prophylactic against coccidiosis[1][2].

Biochem/physiol Actions

Sulfaquinoxaline is an ionophorous antibiotic[2] that inhibits vitamin K epoxidase (epoxide reductase, menadione epoxide reductase) and quinone reductase.

Packaging

10G,25G

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
076M4757V
BCBB7740V
BCBB7740
125H0144
126F0409

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Vanessa Ribeiro Urbano et al.
International journal of environmental research and public health, 18(3) (2021-01-28)
Sulfaquinoxaline (SQX) has been detected in environmental water samples, where its side effects are still unknown. To the best of our knowledge, its oxidation by Fenton and photo-Fenton processes has not been previously reported. In this study, SQX oxidation, mineralization
Lilya Boudriche et al.
Water environment research : a research publication of the Water Environment Federation, 91(11), 1412-1419 (2019-05-06)
This study evaluates the efficiency of sulfate radicals used in advanced oxidation process in water treatment. The targeted pollutant is an antibiotic, sulfaquinoxaline (SQ-Na) sodium, widely used in the veterinary field. The results show a degradation of SQ-Na until 90%
The effect of sulfaquinoxaline administration on metabolism of vitamin A and carotene and on hemoglobin young dairy calves.
M RONNING et al.
Journal of animal science, 9(3), 314-320 (1950-08-01)
H D Chapman
Poultry science, 88(4), 813-815 (2009-03-12)
"Continuous feeding of low concentrations of sulfaquinoxaline for the control of coccidiosis in poultry" by L. C. Grumbles, J. P. Delaplane, and T. C. Higgins [Poult. Sci. (1948) 27:605-608] was the first paper to demonstrate that it was possible to
Ahmad Soleymanpour et al.
Materials science & engineering. C, Materials for biological applications, 58, 504-509 (2015-10-20)
A potentiometric carbon paste sensor was fabricated for determination of sulfaquinoxaline (SQX) based on the use of ion-association complex of sulfaquinoxaline sodium with 2,3,5-triphenyltetrazolium chloride. The proposed sensor exhibited Nernstian slope of 58.4 ± 0.3 mV per decade for sulfaquinoxaline

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