Skip to Content
MilliporeSigma
All Photos(1)

Documents

N5504

Sigma-Aldrich

Naphazoline hydrochloride

Synonym(s):

2-(1-Naphthylmethyl)imidazoline hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C14H14N2 · HCl
CAS Number:
550-99-2
Molecular Weight:
246.74
EC Number:
208-989-2
MDL number:
MFCD00012554
UNSPSC Code:
12352200
PubChem Substance ID:
24278592
NACRES:
NA.77

form

powder

originator

Allergan

SMILES string

Cl.C1CN=C(Cc2cccc3ccccc23)N1

InChI

1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H

InChI key

DJDFFEBSKJCGHC-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Naphazoline hydrochloride is a sympathomimetic agent. It is also considered as a conjunctival decongestant.
α-adrenoceptor agonist; imidazoline receptor agonist; vasoconstrictor.

Features and Benefits

This compound was developed by Allergan. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

N-Acetyl-L-cysteine BioReagent, suitable for cell culture

Sigma-Aldrich

A9165

N-Acetyl-L-cysteine

DL-Dithiothreitol ≥98% (HPLC), ≥99.0% (titration)

Sigma-Aldrich

D0632

DL-Dithiothreitol

Arzu Karakurt et al.
European journal of medicinal chemistry, 57, 275-282 (2012-10-23)
Twenty-three new oxime ester derivatives of nafimidone were synthesized with the prospect of potential anticonvulsant activities. MES and ScM tests were employed for their anticonvulsant activities and rotorod test for neurological deficits. Eighteen compounds were found to be protective against
Eman Y Z Frag et al.
The Analyst, 136(2), 332-339 (2010-10-21)
This paper describes the development of screen-printed (SPE) and carbon paste (CPE) sensors for the rapid and sensitive quantification of naphazoline hydrochloride (NPZ) in pharmaceutical formulations. This work compares the electroactivity of conventional carbon paste and screen-printed carbon paste electrodes
Robert Fuchs et al.
Experimental cell research, 317(20), 2969-2980 (2011-08-20)
Even though the erythroleukemia cell lines K562 and HEL do not express α1-adrenoceptors, some α1-adrenergic drugs influence both survival and differentiation of these cell lines. Since Ca2+ is closely related to cellular homeostasis, we examined the capacity of α1-adrenergic drugs
Shizhong Zhu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 98, 142-147 (2012-09-22)
The fluorescence and ultraviolet spectroscopy were explored to study the interaction between Naphazoline hydrochloride (Naphcon) and bovine serum albumin (BSA) at three different temperatures (292, 301, and 310 K) under imitated physiological conditions. The quenching mechanism of BSA by Naphacon
M Gelardi et al.
Journal of biological regulators and homeostatic agents, 23(2), 79-84 (2009-07-11)
A wide variety of nasal irrigation systems are currently available for improving nasal symptoms, but few studies have compared their effectiveness with respect to patient age and type of nasal disease. This pilot study aims to compare the efficacy of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service