A9165

N-Acetyl-L-cysteine

≥99% (TLC), suitable for cell culture, BioReagent

• Synonym(s): LNAC, NAC
• Linear Formula: HSCH₂CH(NHCOCH₃)CO₂H
• CAS Number: 616-91-1
• Molecular Weight: 163.19
• Beilstein/REAXYS Number: 1724426
• EC Number: 210-498-3
• MDL number: MFCD00004880
• UNSPSC Code: 12352209
• PubChem Substance ID: 24891402
• NACRES: NA.26

Properties

• product name: N-Acetyl-L-cysteine, BioReagent, suitable for cell culture
• product line: BioReagent
• assay: ≥99% (TLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• color: white to off-white
• mp: 106-108 °C (lit.)
• solubility: H₂O: 100 mg/mL (with heating)
• storage temp.: 2-8°C
• SMILES string: CC(=O)N[C@@H](CS)C(O)=O
• InChI: 1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
• InChI key: PWKSKIMOESPYIA-BYPYZUCNSA-N

Description

Application

N-Acetyl-L-cysteine has been used as a component of intestinal basal medium for the culture of mouse intestinal stem cells and also as a component of expansion medium.

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)