Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.
Specificity
Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.
Application
Anti-Lactoferrin antibody produced in rabbit has been used in:
western blotting
indirect immunofluorescence
flow cytometry
enzyme-linked immunosorbent assay (ELISA)
Biochem/physiol Actions
A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.
Physical form
Lyophilized from 0.01 M phosphate buffered saline, pH 7.2
Reconstitution
Reconstitute with 2 ml deionized water.
Disclaimer
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