H9627

Hematoxylin

• Synonym(s): Natural Black 1
• Empirical Formula (Hill Notation): C₁₆H₁₄O₆ · xH₂O
• CAS Number: 517-28-2
• Molecular Weight: 302.28 (anhydrous basis)
• Colour Index Number: 75290
• Beilstein/REAXYS Number: 91400
• EC Number: 208-237-3
• MDL number: MFCD00078111
• UNSPSC Code: 12352204
• PubChem Substance ID: 57654281
• NACRES: NA.32

Properties

• form: powder
• technique(s): titration: suitable
• mp: 200 °C (dec.) (lit.)
• solubility: 95% ethanol: 1 mg/mL
• SMILES string: Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O
• InChI: 1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1
• InChI key: WZUVPPKBWHMQCE-XJKSGUPXSA-N
• Gene Information: rat ... Adora1(29290) , Adora2a(25369)

Description

Application

Hematoxylin has been used for staining gastric cancer tissues, myocardial tissue, heart sections and ovarian nuclei.

Biochem/physiol Actions

Hematoxylin is an organic stain which chelates with metal ions and binds to DNA and RNA. It is used for staining nucleus of the cells. Hematoxylin along with eosin stain is used in the diagnosis of invasion stage in tumors.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves