B8391
Boc-Val-Leu-Gly-Arg p-nitroanilide hydrobromide
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About This Item
Empirical Formula (Hill Notation):
C30H49N9O8 · HBr
CAS Number:
Molecular Weight:
744.68
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
storage temp.
−20°C
SMILES string
Br.CC(C)CC(NC(=O)C(NC(=O)OC(C)(C)C)C(C)C)C(=O)NCC(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc(cc1)N(=O)=O
Substrates
Substrate for horseshoe crab clotting enzyme
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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S Iwanaga et al.
Haemostasis, 7(2-3), 183-188 (1978-01-01)
An endotoxin-activated hemocyte lysate from the horseshoe crab (Tachypleus and Limulus) was found to hydrolyze Bz-Ile-Glu-(gamma-OR)-Gly-Arg-p-nitroanilide (PNA), Bz-Val-Gly-Arg-PNA, Boc-Val-Leu-Gly-Arg-PNA, and Boc-Leu-Gly-Arg-PNA, all of which have the COOH-terminal Gly-Arg sequence. This amidase activity was due to a clottting enzyme contained in
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