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A9795

Sigma-Aldrich

Adenine hydrochloride hydrate

powder, BioReagent, suitable for cell culture

Synonym(s):

6-Aminopurine hydrochloride hydrate

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About This Item

Empirical Formula (Hill Notation):
C5H5N5 · HCl · xH2O
CAS Number:
2922-28-3
Molecular Weight:
171.59 (anhydrous basis)
MDL number:
MFCD00150864
UNSPSC Code:
12352205
PubChem Substance ID:
24891498
NACRES:
NA.75

biological source

synthetic (organic)

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

SMILES string

O.Cl.Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5.ClH.H2O/c6-4-3-5(9-1-7-3)10-2-8-4;;/h1-2H,(H3,6,7,8,9,10);1H;1H2

InChI key

MYRDTAUFFBYTHA-UHFFFAOYSA-N

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Application

Adenine hydrochloride hydrate has been used:
  • As a component of FAD cell culture media
  • In maintaining organotypic cultures for recreating stratified epithelium from primary cell cultures
  • In limbal-corneal epithelial culturing and keratinocytes

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vitronectin supports migratory responses of corneal epithelial cells to substrate bound IGF-I and HGF, and facilitates serum-free cultivation
Ainscough SL, et al.
Experimental Eye Research, 83(6), 1505-1514 (2006)
Functional investigations of keratinocyte stem cells and progenitors at a single-cell level using multiparallel clonal microcultures
Epidem. Inf., 83(6), 13-23 (2010)
Three-dimensional organotypic culture of stratified epithelia
Rhim Andrew D and Rustgi Anil K
Cold Spring Harbor Protocols, 2015(4) (2015)
Felipe Perozzo Daltoe et al.
Brazilian oral research, 34, e033-e033 (2020-04-09)
The aim of our study was to isolate populations of keratinocyte stem cells based on the expression of cell surface markers and to investigate whether the culture could affect their phenotype. keratinocytes from human oral mucosa were sorted based on
Elham Nili et al.
Molecules (Basel, Switzerland), 26(22) (2021-11-28)
A recombinant formulation of silk fibroin containing the arginine-glycine-aspartic acid (RGD) cell-binding motif (RGD-fibroin) offers potential advantages for the cultivation of corneal cells. Thus, we investigated the growth of corneal stromal cells and epithelial cells on surfaces created from RGD-fibroin
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