Skip to Content
MilliporeSigma
All Photos(1)

Documents

07602

Sigma-Aldrich

FSB staining solution

1 % (w/v) in DMSO, fluorescent stain for amyloid

Synonym(s):

1-Fluoro-2,5-bis[(E)-3-carboxy-4-hydroxystyryl]benzene solution, 3,3′-[(2-Fluoro-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis[6-hydroxybenzoic acid] solution

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C24H17FO6
CAS Number:
Molecular Weight:
420.39
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32

form

liquid

concentration

1 % (w/v) in DMSO

UV absorption

λ: 360-380 nm Amax: 0.6-0.9

storage temp.

2-8°C

SMILES string

OC(C1=CC(/C=C/C2=CC=C(/C=C/C3=CC(C(O)=O)=C(O)C=C3)C(F)=C2)=CC=C1O)=O

InChI

1S/C24H17FO6/c25-20-13-16(2-1-14-5-9-21(26)18(11-14)23(28)29)4-8-17(20)7-3-15-6-10-22(27)19(12-15)24(30)31/h1-13,26-27H,(H,28,29)(H,30,31)/b2-1+,7-3+

InChI key

DZXZHGCGNRRJEG-WMWQKROPSA-N

General description

1-Fluoro-2,5-bis[(E)-3-carboxy-4-hydroxystyryl]benzene solution (FSB ) is an amyloid-β peptide (Aβ) specific dye. It is a fluorine analog of 1-Bromo-2,5-bis(3-carboxy-4-hydroxystyryl)benzene (BSB). It also acts as an amyloidophilic fluorescent probe for Aβ.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

188.6 °F

flash_point_c

87 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

FK506 reduces amyloid plaque burden and induces MMP-9 in AβPP/PS1 double transgenic mice.
Hong H S, et al.
Journal of Alzheimer'S Disease, 22(1), 97-105 (2010)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service