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S5632

Supelco

Sulfamethizole

analytical standard, ≥99% (HPLC)

Synonym(s):

4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide, N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide, Sulfamethylthiadiazole

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About This Item

Empirical Formula (Hill Notation):
C9H10N4O2S2
CAS Number:
144-82-1
Molecular Weight:
270.33
Beilstein/REAXYS Number:
255002
EC Number:
205-641-1
MDL number:
MFCD00053363
UNSPSC Code:
41116107
PubChem Substance ID:
329824459
NACRES:
NA.24

grade

analytical standard

Quality Level

100

agency

EPA 1694

assay

≥99% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

InChI

1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)

InChI key

VACCAVUAMIDAGB-UHFFFAOYSA-N

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General description

Sulfamethizole is an antibacterial drug used in the treatment of the urinary tract infections.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamethizole may be used as a reference standard to examine the antibiotic remnants in honey by multianalyte/multiclass ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

pcodes

P280

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV0123
MKCV3152
MKCS0622
MKCR4942
MKCN7577

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Coordination chemistry of sulfamethizole: crystal structures of [Cu (sulfamethizolate) 2 (py) 2 (OH 2)]? H 2 O,[M (sulfamethizolate) 2 (py) 2 (OH 2) 2][M= Co and Ni] and {Cu (sulfamethizolate) 2 (dmf) 2}?.
Borras E, et al.
Polyhedron, 19(15), 1859-1866 (2000)
Development of a rapid method for the determination of antibiotic residues in honey using UPLC-ESI-MS/MS.
Kivrak I, et al.
Food Sci. Technol., 36(1), 90-96 (2016)
Tony L Yaksh et al.
Anesthesiology, 108(5), 938-949 (2008-04-24)
Intrathecal N-methyl-d-aspartate antagonists have antihyperalgesic efficacy. The authors examined toxicity in a canine model of chronic lumbar intrathecal infusion. Dogs (10-16 kg) were prepared with lumbar intrathecal catheters connected to vest-mounted pumps (100 microl/h). In phase 1, stepwise incrementations in
Mark R Sannes et al.
The Journal of infectious diseases, 197(3), 430-434 (2008-01-11)
To determine whether poultry contact/consumption predicts colonization with antimicrobial-resistant Escherichia coli, 567 newly hospitalized patients and 100 vegetarians were assessed microbiologically and epidemiologically. Multivariable analysis showed that poultry contact/consumption, other dietary habits, and antimicrobial use did not significantly predict resistance.
Robert R Muder
Seminars in respiratory and critical care medicine, 28(6), 672-677 (2007-12-21)
Stenotrophomonas (Xanthomonas) maltophilia is a nonfermentative, gram-negative bacillus that is widely distributed in natural and human-made environments. In the nonhospital setting it is an uncommon pathogen, typically causing soft tissue infection of contaminated wounds. In the hospital setting, particularly among
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