PHR1511

Carbachol

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Carbamylcholine chloride, Carbachol
• Linear Formula: NH₂COOCH₂CH₂N(Cl)(CH₃)₃
• CAS Number: 51-83-2
• Molecular Weight: 182.65
• Beilstein/REAXYS Number: 3917459
• EC Number: 200-127-3
• MDL number: MFCD00012011
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823429
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to Ph. Eur. Y0000113; traceable to USP 1092009
• API family: carbachol
• CofA: current certificate can be downloaded
• packaging: pkg of 500 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• InChI: 1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
• InChI key: AIXAANGOTKPUOY-UHFFFAOYSA-N
• Gene Information: human ... CHRM3(1131)

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Carbachol, a synthetic derivative of choline, is a highly efficient miotic agent, which can be used for a long-term therapy of non-congestive wide-angle glaucoma. Its mode of action is primarily stimulating muscarinic receptors and releasing acetylcholine at certain neuroeffector junctions and ganglia.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB3674 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P264 - P301 + P310
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable