05566

D-(+)-Glucuronic acid γ-lactone

analytical standard

• Synonym(s): D-(+)-Glucurono-6,3-lactone, D-Glucurone, D-Glucurono-6,3-lactone, Glucuronolactone
• Empirical Formula (Hill Notation): C₆H₈O₆
• CAS Number: 32449-92-6
• Molecular Weight: 176.12
• Beilstein/REAXYS Number: 83595
• EC Number: 251-053-3
• MDL number: MFCD00135622
• UNSPSC Code: 85151701
• PubChem Substance ID: 329748094
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥99.0% (sum of anomers, GC)
• optical activity: [α]/D +18.8±2°, c = 8% in H₂O (after 1 hr)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤0.5% water
• mp: 172-175 °C (lit.)
• application(s): clinical testing
• format: neat
• SMILES string: O=C([C@@H]([C@@H](O1)[C@H](O)[C@H](O)C1=O)O)[H]
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h1-5,8-10H/t2-,3+,4-,5+/m0/s1
• InChI key: UYUXSRADSPPKRZ-SKNVOMKLSA-N

Description

General description

D-Glucuronic acid γ-lactone is a normal human metabolite produced from glucose as starting material. It serves as a precursor for the synthesis of a number of deoxy sugars.

Application

D-Glucuronic acid γ-lactone has been used as an analytical standard for the analysis of D-glucuronic acid γ-lactone as a component of microbial extracellular polysaccharides in biofilms by high performance liquid chromatography (HPLC) with pulsed amperometric detection (PAD) as well as diode array detection (DAD). D-(+)-Glucuronic acid γ-lactone has been used as a reference standard for the determination of D-(+)-glucuronic acid γ-lactone in energy drinks by ultra-high performance liquid chromatography-triple quadrupole
tandem mass spectrometry (UHPLC-MS/MS).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable