immunofluorescence: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable
isotype
IgG2b
shipped in
wet ice
Specificity
Recognizes the VZV glycoprotein I by indirect immunofluorescence, immuno-precipitation and Western blotting.
Immunogen
Epitope: Glycoprotein I
VZV HZ strain.
Application
Anti-Varicella-Zoster Virus Antibody, Glycoprotein I is an antibody against Varicella-Zoster Virus for use in IF, IP, WB, IH.
Indirect immunofluorescence: on unfixed cells shows both cytoplasmic and membrane pattern. Staining on fixed cells shows only cytoplasmic pattern.
Immunohistochemistry: reactive on formalin fixed tissue.
Western blot
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Research Category Infectious Diseases
Research Sub Category Infectious Diseases - Viral
Physical form
1 mg/mL in 0.02M PB with 0.25M NaCl, pH 7.6, containing 0.1% sodium azide.
Format: Purified
Storage and Stability
Maintain at 2-8°C in undiluted aliquots for up to 12 months.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Varicella-zoster virus (VZV), a double-stranded DNA virus, causes varicella, establishes lifelong latency in ganglionic neurons, and reactivates later in life to cause herpes zoster, commonly associated with chronic pain. The VZV genome is densely packed and produces multitudes of overlapping
Primary varicella-zoster virus (VZV) infection leads to varicella and the establishment of lifelong latency in sensory ganglion neurons. Reactivation of latent VZV causes herpes zoster, which is frequently associated with chronic pain. Latent viral gene expression is restricted to the
Deletion of the varicella-zoster virus large subunit of ribonucleotide reductase impairs growth of virus in vitro.
The Journal of infectious diseases, 223(1), 109-112 (2020-09-10)
To test the hypothesis that varicella-zoster virus (VZV) infection contributes to temporal arteritis pathogenesis, comprehensive in situ analysis was performed on temporal artery biopsies of 38 anterior ischemic optic neuropathy (AION) patients, including 14 (37%) with giant cell arteritis. Biopsies
Mutagenesis of varicella-zoster virus glycoprotein I (gI) identifies a cysteine residue critical for gE/gI heterodimer formation, gI structure, and virulence in skin cells.
Stefan L Oliver,Marvin H Sommer,Mike Reichelt,Jaya Rajamani,Leonssia Vlaycheva-Beisheim et al.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.