1.00314

Hydrochloric acid

37%, Emprove^® ESSENTIAL, Ph. Eur., BP, JP, NF, fuming

• Synonym(s): Hydrochloric acid, Hydrogen chloride solution
• Empirical Formula (Hill Notation): HCl
• CAS Number: 7647-01-0
• Molecular Weight: 36.46
• Beilstein/REAXYS Number: 1098214
• MDL number: MFCD00011324
• UNSPSC Code: 12352301

Properties

• product name: Hydrochloric acid, fuming, 37%, EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF, ChP
• agency: BP; ChP; JP; NF; Ph. Eur.
• Quality Level: 500
• vapor density: 1.3 (vs air)
• vapor pressure: 190 hPa ( 20 °C); 3.23 psi ( 21.1 °C); 7.93 psi ( 37.7 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: 36.5-38.0% (alkalimetric)
• form: liquid
• concentration: 37%
• technique(s): API processing | salt formation: suitable
• pH: <1 (20 °C in H₂O)
• bp: >100 °C (lit.)
• density: 1.070 g/cm³ at 20 °C (lit.); 1.19 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation
• storage temp.: 2-25°C
• SMILES string: Cl
• InChI: 1S/ClH/h1H
• InChI key: VEXZGXHMUGYJMC-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Hydrochloric acid can be used as acidifying agent in a variety of pharmaceutical formulations and processes.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H290,H314,H335
• pcodes: P234 - P261 - P271 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 8B - Non-combustible corrosive hazardous materials
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable