R-013

Risperidone-D₄ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₃D₄H₂₃FN₄O₂
• CAS Number: 1020719-76-9
• Molecular Weight: 414.51
• EC Number: 200-659-6
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: [2H]C([2H])(N1CCC(CC1)c2noc3cc(F)ccc23)C([2H])([2H])C4=C(C)N=C5CCCCN5C4=O
• InChI: 1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3/i9D2,13D2
• InChI key: RAPZEAPATHNIPO-RIEWMPPISA-N

Description

General description

Risperidone, marketed as Risperdal^®, Ridal, or Riscalin, is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, and irritability in autistic children. This new internal standard is suitable for many LC/MS and GC/MS applications including forensic analysis, clinical toxicology, urine drug testing, or isotope dilution methods.

Application

• Efficacy and Safety Profiles of Antipsychotic Drugs as Viewed by Psychiatrists: This comparative analysis of cariprazine and risperiDonein clinical settings provides insights into the effectiveness and tolerability of risperidone, a tricyclic antidepressant, emphasizing its role in psychiatric treatment and drug development strategies (Gvozdeckii et al., 2023).


• Effect of Antipsychotics and Mood Stabilisers on Metabolism in Bipolar Disorder: A network meta-analysis focusing on the impact of medications like risperiDoneon metabolic profiles, crucial for understanding pharmacokinetic behaviors and optimizing therapeutic outcomes in bipolar disorder treatment (Kong et al., 2024).


• Antipsychotic Prescribing: National Findings of Children and Adolescents Attending Mental Health Services in Ireland: This study details the prescribing patterns of antipsychotics, including risperidone, contributing to a better understanding of its use in pediatric psychiatric care and aiding in the development of guidelines for safer and more effective use of antipsychotics in young populations (Driscoll and McCarthy, 2024).


• Antipsychotic Medications and Sleep Problems in Patients with Schizophrenia: Investigates the effects of antipsychotic drugs like risperiDoneon sleep disturbances among schizophrenia patients, supporting research into the comprehensive management of sleep issues associated with psychiatric disorders (Cederlöf et al., 2024).


• Hepatotoxicity to Risperidone: Discusses potential hepatotoxic effects of risperidone, highlighting the importance of monitoring liver function during treatment with this drug, essential for ensuring patient safety in clinical practices (André et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Risperdal is a registered trademark of Johnson & Johnson

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup