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D196800

Sigma-Aldrich

1-Fluoro-2,4-dinitrobenzene

99%

Synonym(s):

2,4-Dinitro-1-fluorobenzene, DNFB, DNPF, FDNB, Sanger reagent

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About This Item

Linear Formula:
(O2N)2C6H3F
CAS Number:
70-34-8
Molecular Weight:
186.10
Beilstein/REAXYS Number:
398632
EC Number:
200-734-3
MDL number:
MFCD00007056
UNSPSC Code:
12352100

assay

99%

refractive index

n20/D 1.569 (lit.)

bp

178 °C/25 mmHg (lit.)

mp

25-27 °C (lit.)

density

1.482 g/mL at 25 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O

InChI

1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChI key

LOTKRQAVGJMPNV-UHFFFAOYSA-N

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Application

Reagent for labeling terminal amino acid groups.[1] Used in the detection of phenols.[2] Suppresses the action potential in nerves.[3] Induces contact hypersensitivity.[4]

replaced by

Product No.
Description
Pricing

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

327.2 °F

flash_point_c

164 °C

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
07522TT
S33116
14823HS
11524JZ
11204DX

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Journal of Chromatography A, 44, 251-251 (1969)
Suppression of the action potential in nerve by nitrobenzene derivatives.
I M Cooke et al.
Proceedings of the National Academy of Sciences of the United States of America, 60(2), 470-477 (1968-06-01)
W R Welches et al.
Biochemistry, 20(3), 512-517 (1981-02-03)
Bacterial luciferase catalyzes the mixed-function oxidation of a long-chain saturated aldehyde and FMNH2 to yield the carboxylic acid, FMN, and blue-green light. The enzyme was inactivated by 2,4-dinitrofluorobenzene (FDNB) with an observed second-order rate constant (k2(obsd) of 157 M-1 min-1
The terminal peptides of insulin.
F SANGER
The Biochemical journal, 45(5), 563-574 (1949-01-01)

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