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A76109

Sigma-Aldrich

3-Amino-1-propanesulfonic acid

97%

Synonym(s):

3APS, Homotaurine, Tramiprosate

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1 G
$46.64
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About This Item

Linear Formula:
H2N(CH2)3SO3H
CAS Number:
3687-18-1
Molecular Weight:
139.17
EC Number:
222-977-4
MDL number:
MFCD00008225
UNSPSC Code:
12352100
PubChem Substance ID:
24891257
NACRES:
NA.22

$46.64

List Price$49.10Save 5%

In StockDetails

Request a Bulk Order

Quality Level

100

assay

97%

form

solid

mp

293 °C (dec.) (lit.)

SMILES string

NCCCS(O)(=O)=O

InChI

1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)

InChI key

SNKZJIOFVMKAOJ-UHFFFAOYSA-N

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Related Categories

Application

Important gabamimetic agent-evokes neurological responses similar to those elicited by γ-aminobutyric acid (GABA).[1][2][3][4]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKBD2107V
MKBD2107
10811MD
23922AO
12818MG

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Francine Gervais et al.
Neurobiology of aging, 28(4), 537-547 (2006-05-06)
Amyloid beta-peptide (Abeta) is a major constituent of senile plaques in Alzheimer's disease (AD). Neurotoxicity results from the conformational transition of Abeta from random-coil to beta-sheet and its oligomerization. Among a series of ionic compounds able to interact with soluble
Eric Martineau et al.
Journal of the American Society for Mass Spectrometry, 21(9), 1506-1514 (2010-06-29)
This paper describes an efficient and reproducible screening method for identifying low molecular weight compounds that bind to amyloid beta peptides (Abeta) peptides using electrospray ionization mass spectrometry (ESI-MS). Low molecular weight compounds capable of interacting with soluble Abeta may
M Foster Olive et al.
European journal of pharmacology, 437(1-2), 55-61 (2002-02-28)
The purpose of the present study was to determine the acute effects of the anticraving compound acamprosate (calcium acetylhomotaurinate) and the closely related compound homotaurine on ethanol intake and ethanol-stimulated dopamine release in the nucleus accumbens. Male rats were treated
Steven M Greenberg et al.
Alzheimer disease and associated disorders, 20(4), 269-274 (2006-11-30)
No treatments have been identified to lower the risk of intracerebral hemorrhage due to cerebral amyloid angiopathy (CAA). A potential approach to prevention is the use of agents that interfere with the pathogenic cascade initiated by the beta-amyloid peptide (Abeta).
Riv. Farmacol. Ter., 7, 155-155 (1976)
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Questions

1–2 of 2 Questions  

  1. What other solvent can dissolve this compound besides water?

    1 answer

    1. This compound can also be dissolved in DMSO. However, the concentration at which it can be dissolved in DMSO has not been determined.

      Helpful?

  2. In which solvent,this compound dissolved except water?

    1 answer

    1. This chemical can also be solubilized in DMSO. The concentration at which it can be solubilized in DMSO is not determined.

      Helpful?

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