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Supelco

(S,S)-(+)-Tetrandrine

98%

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About This Item

Empirical Formula (Hill Notation):
C38H42N2O6
CAS Number:
518-34-3
Molecular Weight:
622.75
Beilstein/REAXYS Number:
877811
MDL number:
MFCD08689909
UNSPSC Code:
12000000
PubChem Substance ID:
24862548

assay

98%

optical activity

[α]20/D +285°, c = 1 in chloroform

mp

219-222 °C (lit.)

SMILES string

COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34

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replaced by

Product No.
Description
Pricing

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Zuguang Ye et al.
Malaria journal, 12, 117-117 (2013-04-04)
In vitro evidence indicates that tetrandrine (TT) can potentiate the action of chloroquine 40-fold against choloquine-resistant Plasmodium falciparum. The key question emanating from that study is "would tetrandine and chloroquine be highly effective in a live Aotus monkey model with
Lihong Liu et al.
Journal of pharmaceutical and biomedical analysis, 61, 252-255 (2011-12-27)
A simple and selective method was developed for the simultaneous determination of tetrandrine and fangchinoline in herbal medicine by HPLC with electrochemical detection (ECD) on a bare glassy carbon electrode. The HPLC separation and ECD conditions have been optimized. The
Xiao-hua Xu et al.
Journal of Zhejiang University. Science. B, 13(11), 867-874 (2012-11-06)
To evaluate the effects of tetrandrine citrate, a novel tetrandrine salt with high water solubility, on the growth of imatinib (IM)-resistant chronic myeloid leukemia (CML) in vitro and in vivo, and reveal action molecular mechanisms. Cell viability in vitro was
Guo-Ying Zuo et al.
Molecules (Basel, Switzerland), 16(12), 9819-9826 (2011-11-26)
The antibacterial activity of two bisbenzylisoquinoline alkaloids, tetrandrine (Tet) and demethyltetrandrine (d-Tet), alone and in combination with the antibiotics ampicillin (AMP), azithromycin (AZM), cefazolin (CFZ) and levofloxacin (LEV) against 10 clinical isolates of staphylococcal chromosomal cassette mec (SCCmec) III type
Xiaolin Li et al.
International journal of nanomedicine, 7, 5183-5190 (2012-10-12)
Paclitaxel (Ptx), one of the most widely used anticancer agents, has demonstrated extraordinary activities against a variety of solid tumors. However, the therapeutic response of Ptx is often associated with severe side effects caused by its nonspecific cytotoxic effects and
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