Deutsche medizinische Wochenschrift (1946), 116(21), 816-818 (1991-05-24)
A 19-year-old and a 50-year-old man who together had cleaned a water-tank as part of their duties in a tank protection and cleaning firm developed that same evening lower abdominal pain, dysuria and haematuria. Cystoscopy revealed haemorrhagic cystitis in both
White leghorn cockerels were fed a diet containing 0, 400, 800 and 1600 ppm of malathion for 90 days. Malathion O,O-dimethyl S-(1,2-dicarbethoxy) ethyl phosphorodithioate) at 800 and 1600 ppm caused a significant decrease in body weights. There was a significant
Xenobiotica; the fate of foreign compounds in biological systems, 20(7), 711-726 (1990-07-01)
1. Because of the low concentration of cytochrome P-450 in avocado fruit, microsomal fractions were prepared using polyethylene glycol aggregation and low-speed centrifugation, thus avoiding the need for high-speed centrifugation of large volumes of post-mitochondrial supernatant. Recoveries of cytochrome P-450
A series of 3-aryl-4-isoxazolecarboxamides identified from a high-throughput screening campaign as novel, potent agonists of the human TGR5 G-protein-coupled receptor is described. Many analogues were readily accessible via solution-phase synthesis which resulted in the rapid identification of key structure-activity relationships
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