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Key Documents

V900412

Sigma-Aldrich

三(羟甲基)甲基甘氨酸

Vetec, reagent grade, ≥99%

同義詞:

N-三(羟甲基)甲基甘氨酸

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About This Item

線性公式:
(HOCH2)3CNHCH2CO2H
CAS號碼:
分子量::
179.17
Beilstein:
1937804
EC號碼:
MDL號碼:
分類程式碼代碼:
12161700
PubChem物質ID:

等級

reagent grade

產品線

Vetec

化驗

≥99%

形狀

crystalline powder

有用的pH值範圍

7.4-8.8

pKa (25 °C)

8.1

SMILES 字串

OCC(CO)(CO)NCC(O)=O

InChI

1S/C6H13NO5/c8-2-6(3-9,4-10)7-1-5(11)12/h7-10H,1-4H2,(H,11,12)

InChI 密鑰

SEQKRHFRPICQDD-UHFFFAOYSA-N

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一般說明

三(羟甲基)甲基甘氨酸是最常用的电泳缓冲液,其负电荷比甘氨酸低。这反过来又有助于它更快地迁移。三(羟甲基)甲基甘氨酸也用于细胞团块的再悬浮。此外,它的高离子强度导致更多的离子运动和更少的蛋白质运动。这有助于在较低百分比的丙烯酰胺凝胶中分离低分子量蛋白质。与甘氨酸-十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)系统相比,三(羟甲基)甲基甘氨酸也被用作拖尾离子,有助于在较低丙烯酰胺浓度下解析小蛋白质。

應用

用于分离低分子量的肽的缓冲剂组分。

法律資訊

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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