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1097909

USP

Cefotaxime sodium salt 钠盐

United States Pharmacopeia (USP) Reference Standard

同義詞:

Cefotaxim sodium salt 钠盐

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About This Item

經驗公式(希爾表示法):
C16H16N5NaO7S2
CAS號碼:
分子量::
477.45
Beilstein:
5711411
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

cefotaxime

製造商/商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI 密鑰

AZZMGZXNTDTSME-JUZDKLSSSA-M

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用


  • Rapid evolutionary change in trait correlations of single proteins: This article explores the rapid evolutionary changes in protein traits, providing a fundamental understanding that can inform biochemical studies using tools like Cefotaxime sodium to influence protein interactions in bacterial cells, enhancing the effectiveness of antibacterial therapies (Dasmeh et al., 2024).

  • Moringa oleifera as a potential antimicrobial against pathogenic Clostridium perfringens isolates in farm animals: Research investigates the antimicrobial properties of Moringa oleifera, with implications for enhancing the efficacy of antibiotic treatments like Cefotaxime sodium in combating bacterial infections in veterinary applications (Ibrahim and Altammar, 2024).

  • In vitro antibacterial activity of antibiotics and plant essential oils against Escherichia coli MTCC443 supported through the molecular docking and pharmacokinetics study: This study examines the synergistic effects of Cefotaxime sodium with plant essential oils against E. coli, highlighting its potential in developing new antibacterial combinations that enhance drug efficacy and reduce resistance (Jain et al., 2024).

  • Efficacy and safety of antibiotics for treatment of leptospirosis: a systematic review and network meta-analysis: This comprehensive review assesses the effectiveness of Cefotaxime sodium among other antibiotics in treating leptospirosis, offering critical insights into its clinical utility and safety profile (Ji et al., 2024).

  • Changing Landscape of Antimicrobial Resistance in Neonatal Sepsis: An in silico Analyses of Multidrug Resistance in Klebsiella pneumoniae: The study discusses the rising challenge of antibiotic resistance, emphasizing the role of Cefotaxime sodium in treating complex cases of neonatal sepsis, thus underlining the need for continuous research into its mechanisms and resistance patterns (Vijayakumar et al., 2024).

生化/生理作用

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

其他說明

Broad spectrum third generation cephalosporin antibiotic.
Sales restrictions may apply.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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