1096586

N-氨基甲酰-L-谷氨酸

United States Pharmacopeia (USP) Reference Standard

• 同義詞: N-Carbamyl-L-glutamic acid
• 經驗公式（希爾表示法）: C₆H₁₀N₂O₅
• CAS號碼: 1188-38-1
• 分子量：: 190.15
• MDL號碼: MFCD00047874
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329749237
• NACRES: NA.24

屬性

• 等級: pharmaceutical primary standard
• API 家族: carglumic acid
• 製造商／商標名: USP
• 應用: pharmaceutical
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: NC(=O)N[C@@H](CCC(O)=O)C(O)=O
• InChI: 1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1
• InChI 密鑰: LCQLHJZYVOQKHU-VKHMYHEASA-N
• 基因資訊: human ... CPS1(1373)

描述

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

• Efficacy of Carglumic Acid in Nutritional Management of N-Acetylglutamate Synthase Deficiency: A study evaluated the effectiveness of Carglumic Acid in the nutritional management of patients with N-Acetylglutamate Synthase deficiency, showing significant improvements in patient outcomes (Singh et al., 2024).



• Real-World Use of Carglumic Acid for Organic Acidurias: An observational study highlighted the real-world application of Carglumic Acid in treating methylmalonic and propionic acidurias, demonstrating beneficial effects in metabolic management (Yap et al., 2024).



• Management of Hyperammonemia in Postpartum Women: Research documented a case of partial N-acetyl glutamate synthase deficiency presenting as postpartum hyperammonemia, with management strategies involving Carglumic Acid (Abou Haidar et al., 2023).



• Genetic Insights from Carglumic Acid Treatment: Research on novel compound heterozygote variants in the CPS1 gene emphasized the lessons learned from clinical management using Carglumic Acid, impacting late onset carbamoyl phosphate synthetase 1 deficiency (Lin et al., 2022).

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

USP issued SDS can be found here.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable