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重要文件

G005454

SFC Analysis of Aminoglutethimide Enantiomers on Astec® Cellulose DMP

application for SFC

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測試參數

column: Astec Cellulose DMP, 25 cm x 4.6 mm I.D., 5 μm particles (51099AST)
mobile phase: [A] CO2; [B] methanol containing 0.1% DEA in CO2; (75:25, A:B)
flow rate: 3 mL/min
pressure: 1740 psi (120 bar)
detector: UV, 230 nm
injection: 5 μL
sample: 2 mg/mL in methanol

適合性

application for SFC

應用

pharmaceutical (small molecule)

分析報告

This application demonstrates the ability of the Astec® Cellulose DMP column to separate Aminoglutethimide enantiomers via Supercritical Fluid Chromatography. DMPC-derivatized cellulose is widely used for chiral separations by SFC, both analytical and prep. The Astec® Cellulose DMP works well in SFC mode, providing rapid separations with excellent selectivity.

法律資訊

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

分析物

描述

    DL-Aminoglutethimide

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