569224-U
Discovery® C18 (5 µm) HPLC Columns
L × I.D. 25 cm × 10 mm, HPLC Column
同義詞:
Discovery RP18 HPLC Column
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About This Item
分類程式碼代碼:
41115700
eCl@ss:
32110501
NACRES:
SB.52
長度 × 內徑:
25 cm × 10 mm
表面積:
300 m2/g
粒徑:
5 μm
基質活性組:
C18 (octadecyl) phase
孔徑:
180 Å
基質:
silica gel, high purity, spherical particle platform
fully porous particle
fully porous particle
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產品名稱
Discovery® C18 高效液相色谱柱, 5 μm particle size, L × I.D. 25 cm × 10 mm
材料
stainless steel column
品質等級
agency
suitable for USP L1
產品線
Discovery®
特點
endcapped
製造商／商標名
Discovery®
包裝
1 ea of
標籤範圍
12% Carbon loading
參數
≤70 °C temp. range
400 bar pressure (5801 psi)
技術
HPLC: suitable
LC/MS: suitable
長度 × 內徑
25 cm × 10 mm
表面積
300 m2/g
表面覆盖率
3 μmol/m2
雜質
<10 ppm metals
基質
silica gel, high purity, spherical particle platform
fully porous particle
基質活性組
C18 (octadecyl) phase
粒徑
5 μm
孔徑
180 Å
工作pH值範圍
2-8
應用
food and beverages
分離技術
reversed phase
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一般說明
Discovery® C18 可用于针对 C18 的任何方法。该色谱柱具有对称的峰形、优良的重现性和稳定性等特点，适用于所有常规和高要求的 C18 方法，是此类方法的理想选择。
應用
- Development and Validation of a Reversed-Phase HPLC Method with UV Detection for the Determination of L-Dopa in Vicia faba L. Broad Beans.: Highlights the application of the Discovery® C18 HPLC Column in developing a method for the accurate quantification of L-Dopa in natural sources, which is essential for studies in neuropharmacology and natural product research (Tesoro et al., 2022).
- Simultaneous estimation of paclitaxel and erlotinib in plasma by liquid chromatography/(+) electrospray tandem mass spectrometry: application in formulation development and pharmacokinetics.: This study employs the Discovery® C18 HPLC Column to enhance the simultaneous analysis of paclitaxel and erlotinib, critical for cancer therapy research and formulation development (Khuroo et al., 2022).
特點和優勢
- 优良的重现性
- 分析酸性和碱性化合物均可获得良好的峰形
- 稳定性好、低流失，适用于 LC-MS 分析
- 能够分离多肽和小分子蛋白质
- 与很多同类 C18 色谱柱相比，疏水性更小，因此分析速度更快
法律資訊
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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A major challenge in selecting an appropriate stationary phase for diastereomeric separation is that it is difficult to predict which of the commercially available stationary phases could achieve the required liquid chromatographic (LC) separation. This work describes the selection and
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A novel isocratic reversed-phase high performance liquid-chromatography/ultraviolet detection method for simultaneous determination of cefdinir and cefixime in human plasma was developed and validated after optimization of various chromatographic conditions and other experimental parameters. Sample preparation based on a simple extraction
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This study presents the optimization of a simple HPLC-UV method for the determination of metformin in human plasma. Ion pair separation followed by UV detection was performed on deproteinized human plasma samples. The separation was carried out on a Discovery
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Modafinil, adrafinil and their related substances were synthesized and analyzed by RP-LC with ESI-MS/MS. The ionization mode, polarity, cone voltage, and chromatographic conditions were evaluated. The optimum LC-MS conditions to obtain fragment ions indispensable for identification of the structures were
相關內容
Discovery C18 and C8 HPLC Columns products offered
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