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Merck
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53848-U

Supelco

Ascentis® Express 90Å C8 (2.7 μm) HPLC Columns

L × I.D. 5 cm × 3 mm, HPLC Column

同義詞:

Core-shell (SPP) Fused Core C8 HPLC column

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About This Item

分類程式碼代碼:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis ® Express C8，2.7μm HPLC 色谱柱, 2.7 μm particle size, L × I.D. 5 cm × 3 mm

材料

stainless steel column

agency

suitable for USP L7

產品線

Ascentis®

特點

endcapped

製造商／商標名

Ascentis®

包裝

1 ea of

參數

60 °C temp. range
600 bar max. pressure (9000 psi)

技術

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

長度 × 內徑

5 cm × 3 mm

表面積

135 m2/g

雜質

<5 ppm metals

基質

Fused-Core particle platform
superficially porous particle

基質活性組

C8 (octyl) phase

粒徑

2.7 μm

孔徑

90 Å

工作pH值範圍

2-9

應用

food and beverages

分離技術

reversed phase

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相關類別

一般說明

通过使用Fused-Core® 粒子技术，Ascentis Express HPLC色谱柱在保持较低的反压力的同时，可以为您提供2μm以下颗粒的高速和高效率。高效率和低背压的结合可使UPLC® （或其他超高压系统）用户，以及常规HPLC用户受益。
访问 Ascentis Express 主页，以获得有关此新色谱柱技术的更多信息。

應用


  • Recent trends in ultra-fast HPLC: new generation superficially porous silica columns: This review explores advancements in high-performance liquid chromatography (HPLC), specifically focusing on the Ascentis® Express C8 column. Highlighting its role in achieving high-efficiency separations due to its design, this column is ideal for rapid, high-resolution chromatographic analysis in pharmaceutical, environmental, and material science applications (Ali et al., 2012).

  • Quality by design approach for the separation of naproxcinod and its related substances by fused core particle technology column: This research employs the Ascentis® Express C8 column, utilizing its high-efficiency and rapid separation capabilities to analyze naproxcinod and its impurities. The study exemplifies the column′s use in pharmaceutical quality control, ensuring drug purity and safety (Inugala et al., 2013).

法律資訊

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
UPLC is a registered trademark of Waters

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
USPL001507
USPL001506
USPL001505
USPL001504
USPL001501

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Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Luigi Silvestro et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(30), 3134-3142 (2010-10-20)
Quantitative methods using LC-MS/MS allow achievement of adequate sensitivity for pharmacokinetic studies with clopidogrel; three such methods, with LLOQs as low as 5 pg/mL, were developed and fully validated according to the well established FDA 2001 guidelines. The chromatographic separations
Han Young Eom et al.
Journal of chromatography. A, 1217(26), 4347-4354 (2010-05-11)
Saikosaponins are triterpene saponins derived from the roots of Bupleurum falcatum L. (Umbelliferae), which has been traditionally used to treat fever, inflammation, liver diseases, and nephritis. It is difficult to analyze saikosaponins using HPLC-UV due to the lack of chromophores.
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when
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文章

Ascentis® Express C8 U/HPLC Columns

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

Chromatograms

application for HPLC

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