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53519-U

Supelco

Ascentis® Express 90 Å RP-Amide (2.7 μm) HPLC Columns

L × I.D. 5 mm × 4.6 mm, HPLC Guard Cartridge, pkg of 3 ea

同義詞:

Core-shell (SPP) Fused Core polar embedded HPLC column

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About This Item

分類程式碼代碼:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis® Express RP-Amide,2.7 μm保护柱芯, 2.7 μm particle size, L × I.D. 5 mm × 4.6 mm, pkg of 3 ea

材料

stainless steel column

agency

suitable for USP L60

產品線

Ascentis®

特點

endcapped

包裝

pkg of 3 ea

技術

HPLC: suitable
LC/MS: suitable

長度 × 內徑

5 mm × 4.6 mm

表面積

135 m2/g

基質

Fused-Core® particle platform
superficially porous particle

基質活性組

amide, alkyl phase

粒徑

2.7 μm

孔徑

90 Å

工作pH值

2-9

應用

food and beverages

分離技術

reversed phase

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相關類別

一般說明

Ascentis Express保护柱可为昂贵的分析柱提供物理(过滤)和化学保护,而不会损害Ascentis Express柱的超高性能。这些Ascentis Express保护柱仅需用手拧紧即可在高达9000 psi(600 bar)的压力下连续使用。无需从流路中卸下保护柱套即可轻松更换保护柱芯。柱芯中填充有Ascentis Express Fused-Core®颗粒。单独订购保护柱套。

應用


  • Polycaprolactone Composite Micro/Nanofibrous Material as an Alternative to Restricted Access Media for Direct Extraction and Separation of Non-Steroidal Anti-Inflammatory Drugs from Human Serum Using Column-Switching Chromatography: This research utilized the Ascentis Express RP-Amide, demonstrating its effectiveness in column-switching chromatography for the extraction and separation of non-steroidal anti-inflammatory drugs directly from human serum. The study highlights the column′s utility in handling complex biological matrices, an essential aspect for pharmacokinetic and drug monitoring studies (Raabova et al., 2021).

  • An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study: This paper details the use of the Ascentis Express RP-Amide in a validated HPLC-MS method for the analysis of PC 48, a novel acetylcholinesterase inhibitor, in rat plasma. The method′s application to pharmacokinetic studies underscores its significance in the development and therapeutic monitoring of new drugs (Mzik et al., 2016).

  • On-line SPE-UHPLC method using fused core columns for extraction and separation of nine illegal dyes in chilli-containing spices: Demonstrating the versatility of the Ascentis Express RP-Amide, this study employed the column in an on-line solid-phase extraction (SPE) coupled with UHPLC to detect illegal dyes in food samples. The method′s robustness and high-throughput capabilities make it ideal for ensuring food safety and compliance with regulatory standards (Khalikova et al., 2014).

法律資訊

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Michael T Furlong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 926, 36-41 (2013-04-02)
Clopidogrel is prescribed for the treatment of Acute Coronary Syndrome and recent myocardial infarction, recent stroke, or established peripheral arterial disease. A sensitive and reliable high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay was developed and validated to enable reliable
Martin Mzik et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1020, 85-89 (2016-04-01)
A simple, rapid and sensitive method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed and validated for the quantitative determination in rat plasma of a new candidate for AD treatment, namely PC 48 (a 7-MEOTA-donepezil like compound) in
Erzsébet Oláh et al.
Journal of chromatography. A, 1217(23), 3642-3653 (2010-04-23)
Today sub-2 microm packed columns are very popular to conduct fast chromatographic separations. The mass-transfer resistance depends on the particle size but some practical limits exist not to reach the theoretically expected plate height and mass-transfer resistance. Another approach applies
Maria A Khalikova et al.
Talanta, 130, 433-441 (2014-08-28)
The presented work describes the development of a simple, fast and effective on-line SPE-UHPLC-UV/vis method using fused core particle columns for extraction, separation and quantitative analysis of the nine illegal dyes, most frequently found in chilli-containing spices. The red dyes
Hirotaka Kushida et al.
Biomedical chromatography : BMC, 27(12), 1647-1656 (2013-07-03)
Uncaria Hook (UH) alkaloids are involved in the beneficial effects of Yokukansan. However, the pharmacokinetics of UH alkaloids after oral administration of Yokukansan has not yet been sufficiently investigated. Therefore, we developed and validated a sensitive and specific high-performance liquid

文章

Improve your separation of basic compounds with our Ascentis® Express RP-Amide HPLC columns from the Supelco® portfolio.

使用 Supelco® 產品組合中的 Ascentis® Express RP-Amide HPLC 色譜柱,改善基本化合物的分離效果。

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