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Astec® CYCLOBOND I 2000 HP-RSP Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

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About This Item

分類程式碼代碼:
41115700
eCl@ss:
32110501
NACRES:
SB.52

產品名稱

Astec® CYCLOBOND I 2000 HP-RSP手性HPLC色谱柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

材料

stainless steel column

品質等級

產品線

Astec®

包裝

pkg of 1 ea

製造商/商標名

Astec®

參數

0-50 °C temperature
172 bar pressure (2500 psi)

技術

HPLC: suitable
LC/MS: suitable

長度 × 內徑

15 cm × 4.6 mm

基質

silica particle platform
fully porous particle

基質活性組

cyclodextrin, beta- phase

粒徑

5 μm

孔徑

100 Å

工作pH值

3.5-7

分離技術

chiral

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一般說明

这种新固定相的设计目的在于开发一种稳定性和重现性良好的键合相,保留时间更短,并具有比 CYCLOBOND I 2000 RSP 更好的选择性。目标完成并超额实现,CYCLOBOND I 2000 HP-RSP 通过增加氢键作用提高了分离能力,为手性筛选提供广泛的手性选择性。它最适合于碱性和中性化合物。

  • 键合相:(R,S)-羟丙基改性的 β-环糊精(高效)

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法律資訊

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

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分析證明 (COA)

Lot/Batch Number

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Assessment of the complexation degree of camptothecin derivatives and cyclodextrins using spectroscopic and separative methodologies
Foulon, C., et al.
Tetrahedron Asymmetry, 20 (21), 2482-2489 (2009)
Reprint of: Enantiomeric separation of functionalized ethano-bridged Troger bases using macrocyclic cyclofructan and cyclodextrin chiral selectors in high-performance liquid chromatography and capillary electrophoresis with application of principal component analysis
Weatherly, Choyce A., et al.
Journal of Chromatography. B, Biomedical Applications, 968, 40-48 (2014)
Roland Török et al.
Journal of chromatography. A, 1098(1-2), 75-81 (2005-11-30)
Direct high-performance liquid chromatographic methods were developed for the enantioseparation of (R,S)-bicalutamide (1) and its analogs (+/-)-3-chloro-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide (2), (+/-)-N-(4-cyano-3-(trifluoro-methyl)phenyl)-2-methyloxirane-2-carboxamide (3), (+/-)-4-fluorophenylsulfonyl-2-hydroxy-2-methylpropionic acid (4) and (+/-)-3-hydroxy-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide (5). The methods involved the use of a cellulose-based Chiralcel OD-H, macrocyclic glycopeptide-based Chirobiotic T
Xinxin Han et al.
Journal of chromatography. A, 1063(1-2), 111-120 (2005-02-11)
The enantiomeric separation of a set of 30 new chiral furan derivatives has been achieved on native and derivatized beta-cyclodextrin stationary phases using high performance liquid chromatography (HPLC). The hydroxypropyl-beta-cyclodextrin (Cyclobond RSP), the 2,3-dimethyl-beta-cyclodextrin (Cyclobond DM), and the acetyl-beta-cyclodextrin (Cyclobond

相關內容

CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.

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