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Merck
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Z373419

LiposoFast脂质体制备聚碳酸酯膜

LiposoFast Liposome Factory

pore size 100 nm, polycarbonate membrane

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About This Item

分類程式碼代碼:
41104900
NACRES:
NB.22
暫時無法取得訂價和供貨情況

材料

polycarbonate membrane

無菌

non-sterile

孔徑

100 nm

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一般說明

快速、有效地制备大小均一的单室脂质体。原理很简单:采用固定在膜包上的特殊改进的气密注射器,来回推动,使得脂质乳液反复通过多孔聚碳酸酯滤膜,从而挤出脂质体。使用提供的注射器,样品处理量为 0.5 mL,样品残留量几乎为零。滤膜可选择孔径:100 至 400 nm。

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分析證明 (COA)

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Questions

  1. Hi : what else aside form the LiposoFast device is needed in terms of equipment , consumables etc.. to run a small yield . And also , what is the total yield final output ? Can be added a water-soluble plant extract for a liposomal-herbal preparation?

    1 answer
    1. This product is not tested for liposome generation from specific sources. The phospholipid sample should be dissolved in an organic solvent initially. The solvent should then be removed by rotary evaporation, such that a film remains. The film is then hydrated with an aqueous phase and resuspended by shaking or a mechanical shaker to produce multilamellar liposomes. This sample is then placed in the extruder. See the images below for component and placement information. In addition, a brief set-up video may be viewed in the following link:
      https://www.avestin.com/index_htm_files/liposofast.mp4

      Helpful?

Reviews

Active Filters

    • Review 1
    • Votes 5
    1 out of 5 stars.

    the filter breaks very easily

    the filter breaks very easily when you are extruding, there is always a hole in the middle, even when extruding gently

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    Helpful?

    1. Response from MilliporeSigma:

      Thank you for your review!
      LiposoFast membranes have a pore size in nanometers as opposed to micrometers. The syringe for the unit is custom fitted and is not interchangeable. In addition to these factors there is also the nature of the sample type to consider.
      We are unable to fully troubleshoot the issue with the details provided. We encourage customers who experience problems with our products to call or email us for additional technical support. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.

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