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重要文件

U6625

Sigma-Aldrich

尿苷-5′-三磷酸酯 三钠盐 水合物

from yeast, Type III, ≥96%

同義詞:

UTP Na3

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About This Item

經驗公式(希爾表示法):
C9H12N2Na3O15P3 · xH2O
CAS號碼:
分子量::
550.09 (anhydrous basis)
Beilstein:
3585234
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
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生物源

yeast

種類

Type III

化驗

≥96%

溶解度

H2O: soluble 50 mg/mL, clear to slightly hazy, colorless

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

InChI 密鑰

MMJGIWFJVDOPJF-LLWADOMFSA-K

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相關類別

應用

UTP已用于研究其对糖尿病患者的骨骼肌细胞的血管舒张作用[1]。UTP 还被用作嘌呤能激动剂来研究 P2Y2 受体在大鼠基底外侧膜上的离子转运功能[2]

生化/生理作用

P2Y 受体激动剂。

準備報告

尿苷 5′-三磷酸三钠盐(UTP Na3)水合物,以 50mg/ml的浓度溶于水,产生澄清至轻微浑浊的无色溶液。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Satyanarayana R Pondugula et al.
BMC research notes, 3, 100-100 (2010-04-20)
The ionic composition of the luminal fluid in the vestibular labyrinth is maintained within tight limits by the many types of epithelial cells bounding the lumen. Regulatory mechanisms include systemic, paracrine and autocrine hormones along with their associated intracellular signal
Xiping Chen et al.
FEBS letters, 595(1), 110-122 (2020-10-25)
O-GlcNAcylation is a post-translational modification catalysed by O-GlcNAc transferase (OGT). Missense mutations in OGT have been associated with developmental disorders, OGT-linked congenital disorder of glycosylation (OGT-CDG), which are characterized by intellectual disability. OGT relies on the hexosamine biosynthetic pathway (HBP)
Alexander Puzenko et al.
The Journal of chemical physics, 137(19), 194502-194502 (2012-11-28)
In this, the third part of our series on the dielectric spectrum symmetrical broadening of water, we consider the nucleotide aqueous solutions. Where in Parts I [E. Levy et al., J. Chem. Phys. 136, 114502 (2012)] and II [E. Levy
Adelaine K W Leung et al.
Journal of molecular biology, 402(1), 154-164 (2010-07-21)
RNA is known to perform diverse roles in the cell, often as ribonucleoprotein (RNP) particles. While the crystal structure of these RNP particles could provide crucial insights into their functions, crystallographic work on RNP complexes is often hampered by difficulties
Lilan You et al.
Cell, 176(1-2), 239-253 (2018-12-07)
Csm, a type III-A CRISPR-Cas interference complex, is a CRISPR RNA (crRNA)-guided RNase that also possesses target RNA-dependent DNase and cyclic oligoadenylate (cOA) synthetase activities. However, the structural features allowing target RNA-binding-dependent activation of DNA cleavage and cOA generation remain

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HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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