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Merck
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重要文件

U3128

Sigma-Aldrich

Uroporphyrin I dihydrochloride

≥95%

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About This Item

經驗公式(希爾表示法):
C40H38N4O16 · 2HCl
CAS號碼:
分子量::
903.67
EC號碼:
MDL號碼:
分類程式碼代碼:
12352300
PubChem物質ID:
NACRES:
NA.22

化驗

≥95%

形狀

powder

反應適用性

core: porphyrin
reagent type: catalyst

儲存溫度

−20°C

SMILES 字串

Cl.Cl.OC(=O)CCc1c(CC(O)=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(CC(O)=O)c5CCC(O)=O)c(CC(O)=O)c4CCC(O)=O)c(CC(O)=O)c3CCC(O)=O

InChI

1S/C40H38N4O16.2ClH/c45-33(46)5-1-17-21(9-37(53)54)29-14-26-19(3-7-35(49)50)23(11-39(57)58)31(43-26)16-28-20(4-8-36(51)52)24(12-40(59)60)32(44-28)15-27-18(2-6-34(47)48)22(10-38(55)56)30(42-27)13-25(17)41-29;;/h13-16,41,44H,1-12H2,(H,45,46)(H,47,48)(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60);2*1H/b25-13-,26-14-,27-15-,28-16-,29-14-,30-13-,31-16-,32-15-;;

InChI 密鑰

DZLKLVAJOHLPKP-ARSPAUKVSA-N

準備報告

Enzymatically prepared

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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S G Afonso et al.
Journal of enzyme inhibition, 10(2), 141-146 (1996-01-01)
The effect of uroporphyrin I (UI) on several cytosolic and mitochondrial enzymes (succinyl CoA synthetase, delta-aminolevulinic acid synthetase, rhodanese, lactate dehydrogenase) has been examined. All the enzymes were inactivated in the presence of the porphyrin both in the dark and
S G Afonso et al.
Journal of enzyme inhibition, 5(3), 225-233 (1991-01-01)
The action of uroporphyrin I (URO I) on the activity of red cell uroporphyrinogen decarboxylase (URO-D) in the dark and under UV light was studied. Light-dependent-and light-independent inactivation was observed. Both effects increased at increasing concentrations of URO I, the
S Afonso et al.
The international journal of biochemistry & cell biology, 30(4), 535-543 (1998-07-24)
Uroporphyrin and protoporphyrin produce alterations on 5-aminolevulinic acid dehydratase and porphobilinogen deaminase, as a result of a direct effect of porphyrins on the protein structure. With the aim of assessing the possible protection from the porphyrins effect on the proteins
Simon Y L Ching et al.
Analytical biochemistry, 353(2), 257-265 (2006-03-28)
Few methods for assessing total antioxidant capacity (TAC) include both the percentage of inhibition and the length of inhibition in the measurement. Available methods require above ambient constant temperature incubation, reaction preheating, and/or separate assays for testing hydrophilic and hydrophobic
G Herrmann et al.
The Journal of investigative dermatology, 107(3), 398-403 (1996-09-01)
Porphyria cutanea tarda is characterized by severe connective tissue damage in sun-exposed skin. The regulated synthesis and degradation of the extracellular matrix by various matrix metalloproteinases (MMPs) determine its amount and composition within the skin. In this study, we therefore

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