推薦產品
化驗
>97% (HPLC)
形狀
powder
顏色
white
mp
114-114.8 °C (lit.)
溶解度
DMSO: >20 mg/mL
SMILES 字串
Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F
InChI
1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3
InChI 密鑰
ZIIUUSVHCHPIQD-UHFFFAOYSA-N
應用
m-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis1. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells2.
生化／生理作用
First known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms).
準備報告
m-3M3FBS is soluble in DMSO at a concentration that is greater than 20 mg/ml.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Ondrej Cerny et al.
Journal of immunology (Baltimore, Md. : 1950), 198(3), 1285-1296 (2017-01-01)
The adenylate cyclase toxin-hemolysin (CyaA) plays a key role in immune evasion and virulence of the whooping cough agent Bordetella pertussis. CyaA penetrates the complement receptor 3-expressing phagocytes and ablates their bactericidal capacities by catalyzing unregulated conversion of cytosolic ATP
Kathryn P Trogden et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(5), 2841-2854 (2018-02-07)
Vimentin is a cytoskeletal intermediate filament protein that is expressed in mesenchymal cells and cancer cells during the epithelial-mesenchymal transition. The goal of this study was to identify vimentin-targeting small molecules by using the Tocriscreen library of 1120 biochemically active
Jieny Gröper et al.
Cells, 9(4) (2020-04-29)
Ligand-based selectivity in signal transduction (biased signaling) is an emerging field of G protein-coupled receptor (GPCR) research and might allow the development of drugs with targeted activation profiles. Human formyl peptide receptor 1 (FPR1) is a GPCR that detects potentially
Shih-Wei Wang et al.
Journal of cellular physiology, 236(5), 3979-3990 (2020-12-01)
Prostate cancer has high metastatic potential. Men with higher urinary levels of the sleep hormone melatonin are much less likely to develop advanced prostate cancer compared with men with lower levels of melatonin. Melatonin has shown anticancer activity in experimental
Alexander B Forster et al.
Molecular pain, 5, 17-17 (2009-04-18)
Morphine and its derivatives are key drugs in pain control. Despite its well-known analgesic properties morphine at high concentrations may be proalgesic. Particularly, short-lasting painful sensations have been reported upon dermal application of morphine. To study a possible involvement of
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