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T1512

Sigma-Aldrich

四咪唑 盐酸盐

powder, ≥99% (TLC)

同義詞:

(±)-2,3,5,6-四氢-6-苯基咪唑并[2,1-b]噻唑 盐酸盐

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About This Item

經驗公式(希爾表示法):
C11H12N2S · HCl
CAS號碼:
分子量::
240.75
Beilstein:
4358989
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

product name

四咪唑 盐酸盐, phosphatase inhibitor

生物源

synthetic (organic)

描述

alkaline phosphatase inhibitor

化驗

≥99% (TLC)

形狀

powder

mp

266-267 °C (lit.)

溶解度

water: 50 mg/mL, clear, colorless

SMILES 字串

Cl[H].C1CN2CC(N=C2S1)c3ccccc3

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H

InChI 密鑰

LAZPBGZRMVRFKY-UHFFFAOYSA-N

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應用

四咪唑衍生物作为碱性磷酸酶抑制剂的结构-活性关系。
适于抑制各种哺乳动物碱性磷酸酶(例如,肝、肾、胎盘、骨和肿瘤)。肠道碱性磷酸酶仅受到轻微的抑制。

其他說明

外消旋形式的左旋咪唑。

相關產品

產品號碼
描述
訂價

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析證明 (COA)

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Lokesh G Pimpale et al.
eLife, 9 (2020-07-10)
Proper positioning of cells is essential for many aspects of development. Daughter cell positions can be specified via orienting the cell division axis during cytokinesis. Rotatory actomyosin flows during division have been implied in specifying and reorienting the cell division
Nicolas T Chartier et al.
Nature physics, 17(8), 920-925 (2021-11-16)
Oocytes are large cells that develop into an embryo upon fertilization1. As interconnected germ cells mature into oocytes, some of them grow-typically at the expense of others that undergo cell death2-4. We present evidence that in the nematode Caenorhabditis elegans
Kinetics and inhibition of alkaline phosphatases from canine tissues.
H Van Belle
Biochimica et biophysica acta, 289(1), 158-168 (1972-11-10)
Omer Yuval et al.
PLoS computational biology, 17(7), e1009185-e1009185 (2021-07-20)
Complex dendritic trees are a distinctive feature of neurons. Alterations to dendritic morphology are associated with developmental, behavioral and neurodegenerative changes. The highly-arborized PVD neuron of C. elegans serves as a model to study dendritic patterning; however, quantitative, objective and
Karla Opperman et al.
Genetics, 199(2), 497-509 (2014-12-10)
The L1CAM family of cell adhesion molecules is a conserved set of single-pass transmembrane proteins that play diverse roles required for proper nervous system development and function. Mutations in L1CAMs can cause the neurological L1 syndrome and are associated with

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